PAC-14028

Base Information

Chemical Name:PAC-14028
CAS No.:932372-01-5
Molecular Formula:C₂₄H₂₇N₃O₇S
Molecular Weight:501.56
Hs Code.:

Synonyms:

Suppliers and Price of PAC-14028

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 12 raw suppliers

Chemical Property of PAC-14028

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of PAC-14028

There total 14 articles about PAC-14028 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: C₂₅H₂₉N₃O₇S

: 932372-01-5
[2-(oxazol-2-yl)-5-(4-{4-[(propan-2-yl)oxy]phenylsulfonyl}piperazine-1-yl)phenoxy]acetic acid

Guidance literature:: C₂₅H₂₉N₃O₇S; With water; sodium hydroxide; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In water; N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

Reference yield:

: 2-(5-(4-((4-isopropoxyphenyl)sulfonyl)piperazin-1-yl)-2-(oxazol-2-yl)phenoxy)acetic acid ethyl ester

: 932372-01-5
[2-(oxazol-2-yl)-5-(4-{4-[(propan-2-yl)oxy]phenylsulfonyl}piperazine-1-yl)phenoxy]acetic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; at 60 ℃; for 1.33333h;

Reference yield:

: 4-chloro-2-hydroxy-N-(2-oxoethyl)benzamide

: 932372-01-5
[2-(oxazol-2-yl)-5-(4-{4-[(propan-2-yl)oxy]phenylsulfonyl}piperazine-1-yl)phenoxy]acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: dichlorotriphenylphosphorane / acetonitrile / 2.67 h / 25 °C

1.2: 4.87 h / 25 °C

1.3: 1 h / 60 °C

2.1: acetic acid / water; toluene; methanol / 1.32 h / 60 °C

2.2: 1 h / 60 °C

3.1: sodium tert-pentoxide; tri-t-butylphosphonium tetraphenylborate complex; palladium diacetate / toluene / 1.5 h / 35 - 110 °C

4.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 230 h / 80 °C

5.1: sodium hydroxide; water / tetrahydrofuran / 1.33 h / 60 °C

With water; palladium diacetate; sodium tert-pentoxide; potassium carbonate; acetic acid; potassium iodide; sodium hydroxide; tri-t-butylphosphonium tetraphenylborate complex; dichlorotriphenylphosphorane; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; toluene; acetonitrile;