trans-3-aminocyclopentane-1-carboxylic acid hydrochloride

Base Information

• Chemical Name: trans-3-aminocyclopentane-1-carboxylic acid hydrochloride
• CAS No.: 1392803-15-4
• Molecular Formula: C₆H₁₁NO₂*ClH
• Molecular Weight: 165.62
• Mol file: 1392803-15-4.mol

Synonyms:trans-3-aminocyclopentane-1-carboxylic acid hydrochloride;trans-3-Aminocyclopentanecarboxylic acid hydrochloride

Chemical Property of trans-3-aminocyclopentane-1-carboxylic acid hydrochloride

Chemical Property:

• PSA: 63.32000
• LogP: 1.70070
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

trans-3-Aminocyclopentanecarboxylicacidhydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-3-aminocyclopentane-1-carboxylic acid hydrochloride

There total 19 articles about trans-3-aminocyclopentane-1-carboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(1R,3R)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid (489446-85-7) → (1R,3R)-3-aminocyclopentane-1-carboxylic acid hydrochloride (1203306-05-1,1392803-15-4,19042-35-4,147780-44-7)

Guidance literature:

(1R,3R)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid; In dichloromethane; at 20 ℃; for 2h;

With hydrogenchloride; In 1,4-dioxane;

Reference yield: 93.0%

2-Azabicyclo[2.2.1]heptan-3-one (24647-29-8) → cis-3-aminocyclopentanecarboxylic acid hydrochloride (1203306-05-1,1392803-15-4,19042-35-4,147780-44-7)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 48h;

DOI:10.1002/anie.200501555

Reference yield: 87.2%

1-azabicyclo[2.2.1]heptan-3-one (21472-89-9) → (1S,3R)-3-aminocyclopentanecarboxylic acid hydrochloride salt (1203306-05-1,1392803-15-4,19042-35-4,147780-44-7)

Guidance literature:

With hydrogenchloride; for 4h; Reflux;

upstream raw materials:

(1S,4R)-N-(9-Phenylfluoren-9-yl)-2-azabicyclo<2.2.1>heptan-3-one

(-)-2-Azabicyclo<2.2.1>heptan-3-one

1-azabicyclo[2.2.1]heptan-3-one

(1S,3R)-3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid

Downstream raw materials:

(1R,3S)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid

(1S,3R)-3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid

(1R,3S)-methyl 3-aminocyclopentanecarboxylate hydrochloride