Cis(1S,2R)-Methyl 3-aMinocyclopentanecarboxylate hydrochloride

Base Information

• Chemical Name: Cis(1S,2R)-Methyl 3-aMinocyclopentanecarboxylate hydrochloride
• CAS No.: 180323-49-3
• Molecular Formula: C₇H₁₃NO₂*ClH
• Molecular Weight: 179.647
• Hs Code.: 2922498590
• Mol file: 180323-49-3.mol

Synonyms:

Chemical Property of Cis(1S,2R)-Methyl 3-aMinocyclopentanecarboxylate hydrochloride

Chemical Property:

• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(1S,3R)-Methyl3-aminocyclopentanecarboxylatehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cis(1S,2R)-Methyl 3-aMinocyclopentanecarboxylate hydrochloride

There total 17 articles about Cis(1S,2R)-Methyl 3-aMinocyclopentanecarboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + (1S,3R)-3-aminocyclopentanecarboxylic acid (71830-07-4) → (1S,3R)-3-amino-cyclopentanecarboxylic acid methyl ester hydrochloride (180323-49-3,222530-45-2,1398534-59-2,222530-29-2)

Guidance literature:

With thionyl chloride; at 18 - 25 ℃; for 2.5h; Cooling with acetone-ice; Heating / reflux;

Reference yield: 100.0%

methanol (67-56-1) + (1R,3S)-3-aminocyclopentanecarboxylic acid (71830-08-5) → (1R,3S)-methyl 3-aminocyclopentanecarboxylate hydrochloride (180323-49-3,222530-45-2,1398534-59-2,222530-29-2)

Guidance literature:

With thionyl chloride; at 0 - 65 ℃; for 20h;

Reference yield: 98.0%

methanol (67-56-1) + (1R,3S)-3-aminocyclopentanecarboxylic acid hydrochloride (1203306-05-1,1392803-15-4,19042-35-4,147780-44-7) → (1R,3S)-methyl 3-aminocyclopentanecarboxylate hydrochloride (180323-49-3,222530-45-2,1398534-59-2,222530-29-2)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃; Inert atmosphere;

upstream raw materials:

methanol

(1R,3S)-3-aminocyclopentanecarboxylic acid hydrochloride

(1S,4R)-N-(9-Phenylfluoren-9-yl)-2-azabicyclo<2.2.1>heptan-3-one

(1R,3S)-3-aminocyclopentanecarboxylic acid

Downstream raw materials:

(1S,3S)-1-(tert-butoxycarbonylamino)cyclopentane-3-carboxylic acid methyl ester