Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate

Base Information

Chemical Name:Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate
CAS No.:1171080-45-7
Molecular Formula:C20H24N2O3.C2H2O4
Molecular Weight:430.458
Hs Code.:
Mol file:1171080-45-7.mol

Synonyms:Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate;2-Piperidinecarboxylic acid, 5-[(phenylmethoxy)amino]-, phenylmethyl ester, (2S,5R)- (ethanedioate);(2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylic acid benzyl ester ethanedioate;(2S,5R)-5-Benzyloxyamino-piperidine-2-carboxylic acid benzyl ester oxalate;(2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic acid phenylmethyl ester ethanedioate;(2S,5R)-Benzyl 5-((benzyloxy)amino)piperidine-2-carboxylate oxalate;benzyl(2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxylateoxalate

Suppliers and Price of Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S,5R)-Benzyl5-((Benzyloxy)amino)piperidine-2-carboxylateOxalate
10mg
$ 45.00

Crysdot
(2S,5R)-Benzyl5-((benzyloxy)amino)piperidine-2-carboxylateoxalate 97%
5g
$ 356.00

ChemScene
2-Piperidinecarboxylicacid,5-[(phenylmethoxy)amino]-,phenylmethylester,(2S,5R)-ethanedioate
5g
$ 202.00

ChemScene
2-Piperidinecarboxylicacid,5-[(phenylmethoxy)amino]-,phenylmethylester,(2S,5R)-ethanedioate
1g
$ 66.00

Chemenu
benzyl(2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxylateoxalate 95+%
1000g
$ 4048.00

Alichem
(2S,5R)-Benzyl5-((benzyloxy)amino)piperidine-2-carboxylateoxalate
5g
$ 400.00

Total 42 raw suppliers

Chemical Property of Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate

Chemical Property:

PSA：134.19000
LogP:2.44710
Storage Temp.:Inert atmosphere,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

(2S,5R)-Benzyl5-((Benzyloxy)amino)piperidine-2-carboxylateOxalate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (2S,5R)-Benzyl 5-((benzyloxy)amino)piperidine-2-carboxylate Oxalate is used as a reactant in the synthesis of Avibactam.

Technology Process of Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate

There total 14 articles about Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1133931-74-4
(2S)-5-(benzyloxyimino)-piperidine-2-carboxylic acid benzyl ester

: 144-62-7,97993-78-7
oxalic acid

: 1171080-45-7,1416134-44-5
(2S,5R)-5-benzyloxyaminopiperidin-2-carboxylic acid benzyl ester oxalic acid salt

Guidance literature:: (2S)-5-(benzyloxyimino)-piperidine-2-carboxylic acid benzyl ester; With sulfuric acid; In ethyl acetate; at -20 - -15 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In ethyl acetate; at -20 - -15 ℃; for 5h;

oxalic acid; In methanol; ethyl acetate; at 45 ℃; for 2h;

Reference yield: 37.7%

: 1133931-68-6
(2S)-5-benzyloxyaminopiperidin-2-carboxylic acid benzyl ester

: 144-62-7,97993-78-7
oxalic acid

: 1171080-45-7,1416134-44-5
(2S,5R)-5-benzyloxyaminopiperidin-2-carboxylic acid benzyl ester oxalic acid salt

Guidance literature:: In methanol; at 0 - 45 ℃; for 6h;

Reference yield:

: 2-benzyl 1-tert-butyl (2S)-5-[(benzyloxy)imino]piperidine-1,2-dicarboxylate

: 144-62-7,97993-78-7
oxalic acid

: 1171080-45-7,1416134-44-5
(2S,5R)-5-benzyloxyaminopiperidin-2-carboxylic acid benzyl ester oxalic acid salt

Guidance literature:: 2-benzyl 1-tert-butyl (2S)-5-[(benzyloxy)imino]piperidine-1,2-dicarboxylate; With sodium tris(acetoxy)borohydride; trifluoroacetic acid; In ethyl acetate; at -5 - 0 ℃; for 6h; Green chemistry; Large scale;

oxalic acid; for 5h; Green chemistry; Large scale;