3-[(dimethylamino)carbonyl]-4-methoxybenzenesulfonyl chloride(SALTDATA: FREE)

Base Information

• Chemical Name: 3-[(dimethylamino)carbonyl]-4-methoxybenzenesulfonyl chloride(SALTDATA: FREE)
• CAS No.: 1114594-34-1
• Molecular Formula: C10H12ClNO4S
• Molecular Weight: 277.72
• Hs Code.: 2924299090
• Mol file: 1114594-34-1.mol

Synonyms:3-[(dimethylamino)carbonyl]-4-methoxybenzenesulfonyl chloride(SALTDATA: FREE)

Chemical Property of 3-[(dimethylamino)carbonyl]-4-methoxybenzenesulfonyl chloride(SALTDATA: FREE)

Chemical Property:

• PSA: 72.06000
• LogP: 2.40530

Purity/Quality:

3-[(Dimethylamino)carbonyl]-4-methoxybenzenesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-[(dimethylamino)carbonyl]-4-methoxybenzenesulfonyl chloride(SALTDATA: FREE)

There total 2 articles about 3-[(dimethylamino)carbonyl]-4-methoxybenzenesulfonyl chloride(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chlorosulfonyl-2-methoxybenzoic acid chloride (69185-96-2) + dimethyl amine (124-40-3) → 3-(dimethylcarbamoyl)-4-methoxybenzene-1-sulfonyl chloride (1114594-34-1)

Guidance literature:

In tetrahydrofuran; toluene; at 0 - 20 ℃;

Reference yield:

5-chlorosulfonyl-2-anisic acid (51904-91-7) → 3-(dimethylcarbamoyl)-4-methoxybenzene-1-sulfonyl chloride (1114594-34-1)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 1 h / 0 - 20 °C

2: tetrahydrofuran; toluene / 0 - 20 °C

With oxalyl dichloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;

Reference yield:

methyl Pyrrole-2-carboxylate (1193-62-0) + 3-(dimethylcarbamoyl)-4-methoxybenzene-1-sulfonyl chloride (1114594-34-1) → methyl 1-(3-(dimethylcarbamoyl)-4-methoxyphenylsulfonyl)-1H-pyrrole-2-carboxylate

Guidance literature:

With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In dichloromethane; water; at 20 ℃; for 24.16h;

upstream raw materials:

5-chlorosulfonyl-2-anisic acid

5-chlorosulfonyl-2-methoxybenzoic acid chloride

dimethyl amine

Refernces

• 1、 -. "DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS". . . Retrieved 2014/01/08.