Methyl 6-nitroquinoline-2-carboxylate

Base Information

Chemical Name:Methyl 6-nitroquinoline-2-carboxylate
CAS No.:112089-59-5
Molecular Formula:C₁₁H₈N₂O₄
Molecular Weight:232.196
Hs Code.:
DSSTox Substance ID:DTXSID40553929
Nikkaji Number:J3.011.599F
Wikidata:Q82434663
Mol file:112089-59-5.mol

Synonyms:METHYL 6-NITROQUINOLINE-2-CARBOXYLATE;112089-59-5;SCHEMBL6965338;DTXSID40553929;AKOS000319925;MB06118

Suppliers and Price of Methyl 6-nitroquinoline-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL-6-NITROQUINOLINE-2-CARBOXYLATE 95.00%
5MG
$ 503.36

Total 2 raw suppliers

Chemical Property of Methyl 6-nitroquinoline-2-carboxylate

Chemical Property:

PSA：85.01000
LogP:2.45280
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:232.04840674
Heavy Atom Count:17
Complexity:315

Purity/Quality:

95% ^*data from raw suppliers

METHYL-6-NITROQUINOLINE-2-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=NC2=C(C=C1)C=C(C=C2)[N+](=O)[O-]

Technology Process of Methyl 6-nitroquinoline-2-carboxylate

There total 3 articles about Methyl 6-nitroquinoline-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6293-83-0
2-iodo-4-nitrophenylamine

: 112089-59-5
methyl 6-nitroquinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; diethylamine / 20 °C / Inert atmosphere

2: copper(ll) bromide / 1,2-dichloro-ethane / 3 h / Inert atmosphere; Reflux

With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; diethylamine; copper(ll) bromide; In 1,2-dichloro-ethane;
DOI:10.1021/ol203360g

Reference yield:

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 613-30-9
2-methyl-6-nitroquinoline

: 112089-59-5
methyl 6-nitroquinoline-2-carboxylate

Guidance literature:: With tert.-butylhydroperoxide; selenium(IV) oxide; Yield given. Multistep reaction; 1.) methylene chloride, 40 deg C, 2 d, 2.) ether, THF;
DOI:10.1021/jm00398a017

Reference yield:

: 77-76-9
2,2-dimethoxy-propane

: 613-30-9
2-methyl-6-nitroquinoline

: 112089-59-5
methyl 6-nitroquinoline-2-carboxylate

Guidance literature:: With hydrogenchloride; tert.-butylhydroperoxide; selenium(IV) oxide; Yield given. Multistep reaction; 1.) methylene chloride, 40 deg C, 2 d, 2.) methanol;
DOI:10.1021/jm00398a017