2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine

Base Information

Chemical Name:2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine
CAS No.:154117-92-7
Molecular Formula:C8H9Cl2N3
Molecular Weight:218.08
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40598739
Wikidata:Q82494541
Mol file:154117-92-7.mol

Synonyms:2,4-dichloro-6-(pyrrolidin-1-yl)pyrimidine;154117-92-7;2,4-dichloro-6-pyrrolidin-1-ylpyrimidine;2,4-dichloro-6-pyrrolidinopyrimidine;SCHEMBL2771738;DTXSID40598739;ZSRQVXSPXHZOAB-UHFFFAOYSA-N;AKOS016845334;SB59048;DA-27296;CS-0358968;J-507143

Suppliers and Price of 2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Dichloro-6-pyrrolidinopyrimidine
10mg
$ 45.00

Crysdot
2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine 95+%
1g
$ 772.00

Chemenu
2,4-dichloro-6-(pyrrolidin-1-yl)pyrimidine 95%
1g
$ 729.00

American Custom Chemicals Corporation
2,4-DICHLORO-6-(PYRROLIDIN-1-YL)PYRIMIDINE 95.00%
5MG
$ 503.60

Alichem
2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine
1g
$ 659.40

Total 13 raw suppliers

Chemical Property of 2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine

Chemical Property:

Boiling Point:359.3±27.0 °C(Predicted)
PKA:-1.02±0.39(Predicted)
PSA：29.02000
Density:1.413±0.06 g/cm3(Predicted)
LogP:2.44860
Storage Temp.:2-8°C
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:217.0173527
Heavy Atom Count:13
Complexity:173

Purity/Quality:

97% ^*data from raw suppliers

2,4-Dichloro-6-pyrrolidinopyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C2=CC(=NC(=N2)Cl)Cl

Technology Process of 2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine

There total 1 articles about 2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 123-75-1
pyrrolidine

: 3764-01-0
2,4,6-trichloropyrimidine

: 154117-92-7
2,4-dichloro-6-(pyrrolidin-1-yl)pyrimidine

: 154117-91-6
4,6-dichloro-2-pyrrolidin-1-yl-pyrimidine

Guidance literature:: With potassium phosphate; at 20 ℃; for 6h; Ionic liquid;
DOI:10.1039/c6gc01742h

Reference yield: 56.0%

: 154117-92-7
2,4-dichloro-6-(pyrrolidin-1-yl)pyrimidine

: 87199-18-6
3-hydroxyphenylboronic acid

: 1354566-52-1
3-(2-chloro-6-pyrrolidin-1-ylpyrimidin-4-yl)phenol

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; at 80 ℃; Inert atmosphere; Alkaline aq. solution;
DOI:10.1021/jm201112g