6-Bromonaphthalen-2-amine hydrochloride

Base Information

• Chemical Name: 6-Bromonaphthalen-2-amine hydrochloride
• CAS No.: 71590-31-3
• Molecular Formula: C10H9BrClN
• Molecular Weight: 258.54216
• Hs Code.: 2921450090
• Mol file: 71590-31-3.mol

Synonyms:6-Bromonaphthalen-2-amine hydrochloride;6-BroMo-2-naphthalenaMine hydrochloride (1:1);6-Bromo-2-naphthalenamine hydrochloride

Chemical Property of 6-Bromonaphthalen-2-amine hydrochloride

Chemical Property:

• PSA: 26.02000
• LogP: 4.56770
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

6-Bromonaphthalen-2-aminehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Bromonaphthalen-2-amine hydrochloride

There total 2 articles about 6-Bromonaphthalen-2-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

6-bromo-2-naphthoic acid (5773-80-8) → 6-bromo-2-aminonaphthalene hydrochloride (71590-31-3)

Guidance literature:

6-bromo-2-naphthoic acid; With diphenyl phosphoryl azide; triethylamine; In tert-butyl alcohol; for 15h; Reflux;

With hydrogenchloride; In methanol; at -78 - 20 ℃; for 15h;

Reference yield:

6-bromo-2-N-tert-butoxycarbonylaminonaphthalene (869114-68-1) → 6-bromo-2-aminonaphthalene hydrochloride (71590-31-3)

Guidance literature:

With hydrogenchloride; In methanol; water; at 20 - 25 ℃; Solvent; Large scale;

Reference yield: 94.0%

6-bromo-2-aminonaphthalene hydrochloride (71590-31-3) + methanesulfonyl chloride (124-63-0) → N-(6-bromonaphthalen-2-yl)-methanesulfonamide (1132940-86-3)

Guidance literature:

With pyridine; In dichloromethane; at 5 ℃; for 3h;

upstream raw materials:

6-bromo-2-naphthoic acid

6-bromo-2-N-tert-butoxycarbonylaminonaphthalene

Downstream raw materials:

N-(6-bromo-[2]naphthyl)-acetamide

6-bromo-naphthalene-1,2-diamine

N-acetyl-1-nitro-6-bromonaphthalene

C₃₉H₄₈N₆O₄Si