5,6-Dichloroquinoline

Base Information

Chemical Name:5,6-Dichloroquinoline
CAS No.:606-42-8
Molecular Formula:C₉H₅Cl₂N
Molecular Weight:198.051
Hs Code.:
DSSTox Substance ID:DTXSID00512936
Nikkaji Number:J79.717K
Wikidata:Q82372391
Mol file:606-42-8.mol

Synonyms:5,6-Dichloroquinoline;606-42-8;SCHEMBL14323414;DTXSID00512936;FT-0714926

Suppliers and Price of 5,6-Dichloroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5,6-Dichloroquinoline

Chemical Property:

Melting Point:84.4-85.1 °C
Boiling Point:311.1±22.0 °C(Predicted)
PKA:3.10±0.15(Predicted)
PSA：12.89000
Density:1.407±0.06 g/cm3(Predicted)
LogP:3.54160
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:196.9799046
Heavy Atom Count:12
Complexity:163

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=C2Cl)Cl)N=C1

Technology Process of 5,6-Dichloroquinoline

There total 9 articles about 5,6-Dichloroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56-81-5,25618-55-7,64333-26-2,8013-25-0
glycerol

: 95-76-1
m,p-dichloroaniline

: 40635-11-8
6.7-Dichlor-chinolin

: 606-42-8
5,6-dichloro-quinoline

Guidance literature:: With sulfuric acid; sodium 3-nitrobenzenesulfonate; In water; at 150 ℃;

Reference yield:

: 333383-84-9
N-(3,4-dichloro-phenyl)-N-(3-oxo-propyl)-methanesulfonamide

: 40635-11-8
6.7-Dichlor-chinolin

: 606-42-8
5,6-dichloro-quinoline

Guidance literature:: N-(3,4-dichloro-phenyl)-N-(3-oxo-propyl)-methanesulfonamide; With trifluorormethanesulfonic acid; In dichloromethane; at 20 ℃; for 0.166667h;

With potassium hydroxide; In dimethyl sulfoxide; at 80 ℃;

Reference yield:

: 17847-44-8
N-(3,4-dichlorophenyl)methanesulfonamide

: 606-42-8
5,6-dichloro-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1.1: Et₃N / methanol

2.1: TfOH / CH₂Cl₂ / 0.17 h / 20 °C

2.2: KOH / dimethylsulfoxide / 80 °C

With trifluorormethanesulfonic acid; triethylamine; In methanol; dichloromethane; 1.1: Michael addition;