[α-[(Trimethylsilyl)amino]phenethyl]phosphonic acid bis(trimethylsilyl) ester

Base Information

• Chemical Name: [α-[(Trimethylsilyl)amino]phenethyl]phosphonic acid bis(trimethylsilyl) ester
• CAS No.: 53122-00-2
• Molecular Weight: 417.7
• Mol file: 53122-00-2.mol

Synonyms:[α-[(Trimethylsilyl)amino]phenethyl]phosphonic acid bis(trimethylsilyl) ester

Chemical Property of [α-[(Trimethylsilyl)amino]phenethyl]phosphonic acid bis(trimethylsilyl) ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

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Technology Process of [α-[(Trimethylsilyl)amino]phenethyl]phosphonic acid bis(trimethylsilyl) ester

There total 1 articles about [α-[(Trimethylsilyl)amino]phenethyl]phosphonic acid bis(trimethylsilyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-amino-2-phenylethanephosphonic acid (6324-00-1) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → Tri-N,O,O-(trimethylsilyl)-1-amino-2-phenylaethyl-phosphonsaeure (53122-00-2)

Guidance literature:

Yield given;

Reference yield:

N-benzyloxycarbonylalanine (4132-86-9,26607-51-2,1142-20-7) + Tri-N,O,O-(trimethylsilyl)-1-amino-2-phenylaethyl-phosphonsaeure (53122-00-2) → [1-(2-Benzyloxycarbonylamino-propionylamino)-2-phenyl-ethyl]-phosphonic acid

Guidance literature:

With water; chloroformic acid ethyl ester; triethylamine; Multistep reaction;

Reference yield:

Tri-N,O,O-(trimethylsilyl)-1-amino-2-phenylaethyl-phosphonsaeure (53122-00-2) + 2(S)-{(benzyloxycarbonyl)amino}-3,3-dimethylbutanoic acid (68222-59-3) → [1-(2-Benzyloxycarbonylamino-3,3-dimethyl-butyrylamino)-2-phenyl-ethyl]-phosphonic acid

Guidance literature:

With water; chloroformic acid ethyl ester; triethylamine; Multistep reaction;

upstream raw materials:

1-amino-2-phenylethanephosphonic acid

1,1,1,3,3,3-hexamethyl-disilazane

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