(3R,4S)-4-Amino-1-boc-3-methoxypiperidine

Base Information

Chemical Name:(3R,4S)-4-Amino-1-boc-3-methoxypiperidine
CAS No.:1171124-68-7
Molecular Formula:C₁₁H₂₂N₂O₃
Molecular Weight:230.307
Hs Code.:
European Community (EC) Number:851-910-7
Mol file:1171124-68-7.mol

Synonyms:1363378-22-6;(3R,4S)-4-AMINO-1-BOC-3-METHOXYPIPERIDINE;tert-butyl (3R,4S)-4-amino-3-methoxypiperidine-1-carboxylate;(3R,4S)-tert-Butyl 4-amino-3-methoxypiperidine-1-carboxylate;1171124-68-7;cis-4-Amino-1-Boc-3-methoxy-piperidine;Cis-4-Amino-1-Boc-3-methoxypiperidine;CIS-4-AMINO-3-METHOXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;SCHEMBL17181323;QNGHCFVWYKWWMU-DTWKUNHWSA-N;MFCD22415234;AKOS025290233;AS-34612;CS-0048556;(3R,4S)-tert-Butyl4-amino-3-methoxypiperidine-1-carboxylate;tert-butyl cis(+/-)-4-amino-3-methoxypiperidine-1-carboxylate;4-Amino-3-methoxy-piperidine-1-carboxylic acid tert-butyl ester;(rac)-cis-4-amino-3-methoxy-piperidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of (3R,4S)-4-Amino-1-boc-3-methoxypiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
cis-4-Amino-1-Boc-3-methoxypiperidine
1 g
$ 825.00

SynQuest Laboratories
cis-4-Amino-1-Boc-3-methoxypiperidine
250 mg
$ 225.00

Matrix Scientific
cis-4-Amino-1-Boc-3-methoxypiperidine
1g
$ 315.00

J&W Pharmlab
cis-4-Amino-1-Boc-3-methoxy-piperidine 98%
1g
$ 250.00

J&W Pharmlab
cis-4-Amino-1-Boc-3-methoxy-piperidine 98%
500mg
$ 175.00

J&W Pharmlab
cis-4-Amino-1-Boc-3-methoxy-piperidine 98%
5g
$ 798.00

Chemenu
cis-4-amino-1-boc-3-methoxypiperidine 97%
25g
$ 1007.00

Chemenu
cis-4-amino-1-boc-3-methoxypiperidine 97%
5g
$ 330.00

Chemenu
cis-4-amino-1-boc-3-methoxypiperidine 97%
10g
$ 528.00

AK Scientific
Cis-4-Amino-1-Boc-3-methoxypiperidine
1g
$ 475.00

Total 29 raw suppliers

Chemical Property of (3R,4S)-4-Amino-1-boc-3-methoxypiperidine

Chemical Property:

Boiling Point:306.2±42.0 °C(Predicted)
PKA:9.42±0.40(Predicted)
PSA：64.79000
Density:1.07±0.1 g/cm3(Predicted)
LogP:1.60770
Storage Temp.:2-8°C(protect from light)
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:230.16304257
Heavy Atom Count:16
Complexity:250

Purity/Quality:

99%, ^*data from raw suppliers

cis-4-Amino-1-Boc-3-methoxypiperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C(C1)OC)N
Isomeric SMILES:CC(C)(C)OC(=O)N1CC[C@@H]([C@@H](C1)OC)N

Technology Process of (3R,4S)-4-Amino-1-boc-3-methoxypiperidine

There total 12 articles about (3R,4S)-4-Amino-1-boc-3-methoxypiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: tert-butyl (3S,4R)-4-{[(benzyloxy)carbonyl]amino}-3-methoxypi peridine-1-carboxylate

: 1171125-92-0,1171124-68-7,1232059-97-0
tert-butyl (3S,4R)-4-amino-3-methoxypiperidine-1-carboxylate

Guidance literature:: With palladium 10% on activated carbon; In methanol; at 20 ℃; for 1.3h; Inert atmosphere;

Reference yield: 94.0%

: (3R,4R)-tert-butyl 4-azido-3-methoxypiperidine-1-carboxylate

: 1171124-68-7,1232059-97-0
(3R,4R)-tert-butyl 4-amino-3-methoxypiperidine-1-carboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol;
DOI:10.1021/acs.jmedchem.5b00773

Reference yield:

: 1188265-31-7
3-methoxy-4-oxopiperidine-1-carboxylic acid t-butyl ester

: 1260639-98-2,1171124-68-7,1232059-97-0
tert-butyl 4-amino-3-methoxypiperidine-1-carboxylate

Guidance literature:: 3-methoxy-4-oxopiperidine-1-carboxylic acid t-butyl ester; With ammonium acetate; sodium cyanoborohydride; In methanol; at 20 ℃; for 4h;

With water; sodium hydroxide; pH=10;