N-(2-Chloroethyl)benzenemethanimine

Base Information

• Chemical Name: N-(2-Chloroethyl)benzenemethanimine
• CAS No.: 70509-19-2
• Molecular Formula: C9H10ClN
• Molecular Weight: 167.64
• Mol file: 70509-19-2.mol

Synonyms:2-Chloro-N-(phenylmethylene)ethanamine;N-(2-Chloroethyl)benzenemethanimine

Chemical Property of N-(2-Chloroethyl)benzenemethanimine

Chemical Property:

• Boiling Point: 90 °C(Press: 0.8 Torr)
• PKA: 4.32±0.50(Predicted)
• PSA: 12.36000
• Density: 0.7940 g/cm3
• LogP: 2.34430

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-Chloroethyl)benzenemethanimine

There total 2 articles about N-(2-Chloroethyl)benzenemethanimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-chloroethanamine hydrochloride (870-24-6) + benzaldehyde (100-52-7) → N‐(2‐chloroethyl)‐1‐phenylmethanimine (70509-19-2)

Guidance literature:

With magnesium sulfate; triethylamine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/jo1020932

Reference yield:

N-(2-chloroethyl)-4,4,5,5-tetramethyl-N-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolan-2-amine + benzaldehyde (100-52-7) → N‐(2‐chloroethyl)‐1‐phenylmethanimine (70509-19-2)

Guidance literature:

In chloroform-d1; at 50 ℃; for 5h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1002/chem.202000753

Reference yield: 70.0%

N‐(2‐chloroethyl)‐1‐phenylmethanimine (70509-19-2) → 1-phenyl-2-aza-1,3-butadiene (70509-11-4)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; for 3h;

upstream raw materials:

2-chloroethanamine hydrochloride

benzaldehyde

Downstream raw materials:

1-phenyl-3-methoxy-2-aza-1-butene

1-phenyl-2-aza-1,3-butadiene

N,N,N',N'-tetramethyl-C-phenylmethanediamine

1-phenyl-3-ethoxy-2-aza-1-butene