N-[(Benzyloxy)carbonyl]-L-glutamic acid 1-hydrazide

Base Information

• Chemical Name: N-[(Benzyloxy)carbonyl]-L-glutamic acid 1-hydrazide
• CAS No.: 5707-87-9
• Molecular Formula: C₁₃H₁₇N₃O₅
• Molecular Weight: 295.295
• Mol file: 5707-87-9.mol

Synonyms:N-[(Benzyloxy)carbonyl]-L-glutamic acid 1-hydrazide

Chemical Property of N-[(Benzyloxy)carbonyl]-L-glutamic acid 1-hydrazide

Chemical Property:

• PSA: 130.75000
• LogP: 1.61820

Purity/Quality:

95% ^*data from raw suppliers

Z-L-Glu-NHNH2 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-[(Benzyloxy)carbonyl]-L-glutamic acid 1-hydrazide

There total 5 articles about N-[(Benzyloxy)carbonyl]-L-glutamic acid 1-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4S)-4-{[(benzyloxy)carbonyl]amino}-5-ethoxy-5-oxopentanoic acid (5672-81-1) → N-benzyloxycarbonyl-L-glutamic acid-1-hydrazide (5707-87-9)

Guidance literature:

With water; hydrazine hydrate; at 70 ℃;

Reference yield:

N-(benzyloxycarbonyl)-L-glutamic acid anhydride (4124-76-9) → N-benzyloxycarbonyl-L-glutamic acid-1-hydrazide (5707-87-9) + N-benzyloxycarbonyl-L-glutamic acid dihydrazide (6948-48-7)

Guidance literature:

With ethanol; at 100 ℃; Behandeln des Reaktionsprodukts mit N₂H₄+H₂O in Aethanol;

Reference yield:

N-(benzyloxycarbonyl)-L-glutamic acid anhydride (4124-76-9) → N-benzyloxycarbonyl-L-glutamic acid-1-hydrazide (5707-87-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 120 - 130 °C

2: ethanol; N₂H₄+H₂O

With ethanol; hydrazine hydrate;

DOI:10.1039/jr9500001954

upstream raw materials:

(4S)-4-{[(benzyloxy)carbonyl]amino}-5-ethoxy-5-oxopentanoic acid

N-(benzyloxycarbonyl)-L-glutamic acid anhydride

Carbobenzoxy-L-glutaminsaeure-1-thioethylester

N-benzyloxycarbonyl-L-glutamic acid