3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline

Base Information

Chemical Name:3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline
CAS No.:1256360-50-5
Molecular Formula:C15H22BNO2
Molecular Weight:259.15168
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10682371
Wikidata:Q82606728
Mol file:1256360-50-5.mol

Synonyms:1256360-50-5;3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline;5,6,7,8-tetrahydroquinoline-3-boronic acid, pinacol ester;5,6,7,8-Tetrahydroquinoline-3-boronic acid pinacol ester;SCHEMBL14654811;5,6,7,8-Tetrahydroquinoline-3-boronic acid,pinacol ester;DTXSID10682371;JNIVVYUCVMLVLP-UHFFFAOYSA-N;MFCD17926521;AKOS022184094;BS-26881;CS-0102353;F53769;EN300-2009069;Z2049768707;3-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-5,6,7,8-TETRAHYDROQUINOLINE

Suppliers and Price of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5,6,7,8-Tetrahydroquinoline-3-boronicacid,pinacolester
50mg
$ 130.00

Crysdot
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline 95+%
1g
$ 447.00

AK Scientific
5,6,7,8-Tetrahydroquinoline-3-boronicacidpinacolester
1g
$ 684.00

Total 12 raw suppliers

Chemical Property of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline

Chemical Property:

PSA：31.35000
LogP:2.25960
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:259.1743591
Heavy Atom Count:19
Complexity:329

Purity/Quality:

97% ^*data from raw suppliers

5,6,7,8-Tetrahydroquinoline-3-boronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(CCCC3)N=C2

Technology Process of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline

There total 1 articles about 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10500-57-9
5,6,7,8-tetrahydroquinoline

: 73183-34-3
bis(pinacol)diborane

: 1256360-50-5
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline

Guidance literature:: With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine; In tetrahydrofuran; at 75 ℃; for 11h; Inert atmosphere;
DOI:10.1002/anie.201208297

Reference yield: 99.0%

: 1256360-50-5
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6,7,8-tetrahydroquinoline

: 2-((trans-4-hydroxycyclohexyl)amino)-4-(4-iodo-3-isopropyl-1H-pyrazolo[3,4-b]pyridin-1-yl)benzonitrile

: 1260536-88-6
2-((trans-4-hydroxycyclohexyl)amino)-4-(3-isopropyl-4-(5,6,7,8-tetrahydroquinolin-3-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)benzonitrile

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; at 100 ℃; for 4h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.8b01085