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82132-68-1

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82132-68-1 Usage

General Description

3-Bromo-5,6,7,8-tetrahydroquinoline is a chemical compound with a molecular formula of C9H10BrN that is commonly used in the synthesis of pharmaceuticals and other organic compounds. It is a heterocyclic compound containing a quinoline ring system with a bromine atom attached at the third position. QUINOLINE, 3-BROMO-5,6,7,8-TETRAHYDRO- has a wide range of applications in medicinal chemistry, particularly in the development of new drugs for various diseases. It is also used as an intermediate in the synthesis of other complex organic molecules. 3-Bromo-5,6,7,8-tetrahydroquinoline is an important building block in chemical synthesis and has significant value in the pharmaceutical and chemical industries.

Check Digit Verification of cas no

The CAS Registry Mumber 82132-68-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,1,3 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 82132-68:
(7*8)+(6*2)+(5*1)+(4*3)+(3*2)+(2*6)+(1*8)=111
111 % 10 = 1
So 82132-68-1 is a valid CAS Registry Number.

82132-68-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Bromo-5,6,7,8-tetrahydroquinoline

1.2 Other means of identification

Product number -
Other names 3-bromo-5,6,7,8-tetrahydro-4-quinolinane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82132-68-1 SDS

82132-68-1Relevant articles and documents

Competent Route to Unsymmetric Dimer Architectures: Total Syntheses of (?)-Lycodine and (?)-Complanadines A and B, and Evaluation of Their Neurite Outgrowth Activities

Zhao, Le,Tsukano, Chihiro,Kwon, Eunsang,Shirakawa, Hisashi,Kaneko, Shuji,Takemoto, Yoshiji,Hirama, Masahiro

supporting information, p. 802 - 812 (2017/02/05)

Valuable synthetic routes to the Lycopodium alkaloid lycodine (1) and its unsymmetric dimers, complanadines A (4) and B (5), have been developed. Regioselective construction of the bicyclo[3.3.1]nonane core structure of lycodine was achieved by a remote functionality-controlled Diels–Alder reaction and subsequent intramolecular Mizoroki–Heck reaction. A key coupling reaction of the lycodine units, pyridine N-oxide (66) and aryl bromide (65), through C?H arylation at the C1 position of 66 provided the unsymmetric dimer structure at a late stage of the synthesis. This strategy greatly simplified the construction of the dimeric architecture and functionalization. Complanadines A (4) and B (5) were synthesized by adjusting the oxidation level of the bipyridine mono-N-oxide (67). The diverse utility of this common intermediate (67) suggests a possible biosynthetic pathway of complanadines in Nature. Both enantiomers of lycodine (1) and complanadines A (4) and B (5) were prepared in sufficient quantities for biological evaluation. The effect on neuron differentiation of PC-12 cells upon treatment with culture medium, in which human astrocytoma cells had been cultured in the presence of 1, 4, or 5 was evaluated.

Total syntheses of complanadines A and B

Zhao, Le,Tsukano, Chihiro,Kwon, Eunsang,Takemoto, Yoshiji,Hirama, Masahiro

supporting information, p. 1722 - 1725 (2013/04/10)

Twice as nice: Total syntheses of dimeric alkaloids, (-)-complanadines A (1) and B (2), were achieved from (-)-lycodine. The unsymmetrical motif was assembled through direct arylation of the pyridine N-oxide. The absolute configuration and specific rotations of complanadines A and B were identified. Cbz=Benzyloxycarbonyl. Copyright

N-aryl-piperazinealkanamides useful for improving sleep

-

, (2008/06/13)

A method of improving sleep in warm-blooded animals suffering from sleep disorders, which method comprises the administration of particular N-aryl-piperazinealkanamide derivatives and compositions containing the same. Novel N-aryl-piperazinealkanamide derivatives.

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