4-(3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-Methylpropyl)phenol

Base Information

Chemical Name:4-(3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-Methylpropyl)phenol
CAS No.:375856-62-5
Molecular Formula:C22H29NO2
Molecular Weight:339.47116
Hs Code.:
Mol file:375856-62-5.mol

Synonyms:4-(3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-Methylpropyl)phenol

Suppliers and Price of 4-(3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-Methylpropyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 4-(3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-Methylpropyl)phenol

Chemical Property:

Boiling Point:512.4±45.0 °C(Predicted)
PKA:10.01±0.26(Predicted)
PSA：43.70000
Density:1.116±0.06 g/cm3(Predicted)
LogP:3.95430

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 4-(3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-Methylpropyl)phenol

There total 4 articles about 4-(3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-Methylpropyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 375856-61-4
3-(4-benzyl-piperidin-1-yl)-1-(4-hydroxy-phenyl)-2-methyl-propan-1-one

: 375856-62-5,169197-03-9
threo-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 ℃;
DOI:10.1016/S0960-894X(01)00392-4

Reference yield:

: 23239-75-0
4-benzylpiperidin-1-ium chloride

: 375856-62-5,169197-03-9
threo-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / 80 °C

2: NaBH₄ / ethanol / 20 °C

With sodium tetrahydroborate; In ethanol; N,N-dimethyl-formamide; 1: Mannich condensation;
DOI:10.1016/S0960-894X(01)00392-4

Reference yield:

: 70-70-2
4-hydroxypropiophenone

: 375856-62-5,169197-03-9
threo-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / 80 °C

2: NaBH₄ / ethanol / 20 °C

With sodium tetrahydroborate; In ethanol; N,N-dimethyl-formamide; 1: Mannich condensation;
DOI:10.1016/S0960-894X(01)00392-4