23239-75-0

Usage

Uses

Used in Pharmaceutical Research and Development:
4-(PHENYLMETHYL)-PIPERIDINE HYDROCHLORIDE is used as a research compound for the development of new medications targeting dopamine-related disorders, due to its selective dopamine reuptake inhibition properties.
Used in Psychiatric Disorders Treatment:
In the field of psychiatry, 4-(PHENYLMETHYL)-PIPERIDINE HYDROCHLORIDE is used as a potential therapeutic agent for the treatment of psychiatric disorders, leveraging its ability to modulate dopamine levels in the brain.
Used in Addictive Behaviors Treatment:
4-(PHENYLMETHYL)-PIPERIDINE HYDROCHLORIDE is used as a potential treatment for addictive behaviors, given its influence on dopamine pathways that are implicated in the reward and reinforcement mechanisms associated with addiction.
Used in Preclinical Studies:
In preclinical research, 4-(PHENYLMETHYL)-PIPERIDINE HYDROCHLORIDE is used as a candidate compound to explore its efficacy and safety in modulating dopamine levels, providing insights into its potential as a new medication for various dopamine-related conditions.

InChI:InChI=1/C12H17N.ClH/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12;/h1-5,12-13H,6-10H2;1H

Upstream product

• 14548-46-0 4-Benzoylpyridine 
• 234111-13-8 3-bromo-α-phenyl-4-pyridinemethanol 
• 100-52-7 benzaldehyde 
• 626-55-1 3-Bromopyridine 

Downstream Products

• 78888-67-2 N-{4-[2-(4-Benzyl-piperidin-1-ylmethyl)-acryloyl]-phenyl}-benzamide; hydrochloride 
• 78888-59-2 2-(4-Benzyl-piperidin-1-ylmethyl)-1-(4-nitro-phenyl)-propenone; hydrochloride 
• 202865-89-2 1-(4-Benzyl-piperidin-1-yl)-cyclohexanecarbonitrile 
• 202865-91-6 1-(4-Benzyl-piperidin-1-yl)-4-methyl-cyclohexanecarbonitrile 
• 125706-63-0 6-(4-Benzyl-piperidin-1-ylmethyl)-1,2-dimethoxy-6,7,8,9-tetrahydro-benzocyclohepten-5-one 
• 71699-78-0 bis(4-benzylpiperidinium) hexachlorodicuprate 
• 71661-75-1 2Cu⁽²⁺⁾*2Cl^(1-)*4Br^(1-)*2C₆H₅CH₂C₅H₁₁N⁽¹⁺⁾=Cu₂Cl₂Br₄(C₆H₅CH₂C₅H₁₁N)2 

Relevant academic research and scientific papers

Scalable and Straightforward Synthesis of All Isomeric (Cyclo)alkylpiperidines

An efficient approach towards introducing (cyclo)alkyl substituents at C-2, C-3 or C-4 positions of the piperidine ring was described. The method relied on the straightforward two-step reaction sequence based on the formal sp3–sp3 re

Controlling chemoselective transformations of 4-acylpyridines via a Pd-C catalytic hydrodechlorination-hydrogenation

A novel Pd-C catalytic hydrodechlorination-hydrogenation was developed for a multi-step one-pot transformation of 4-acylpyridines. Under the selected conditions, 4-benzoylpyridines and 4-alkanoylpyridines were chemoselectively converted into the corresponding 4-benzylpiperidine hydrochlorides and α-alkyl-4-piperidinemethanol hydrochlorides, respectively. This catalytic method was performed simply by an addition of 1 equiv of ClCH 2CHCl2 to the conventional hydrogenation system and directly gave the crystalline piperidine hydrochlorides in practical quantitative yields.

Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

The present invention is a piperazinylalkylbenzofuran derivative of the formula wherein R1 represents a C1-4 alkyl group, R2 stands for a hydrogen atom, X means an oxygen atom, Y is a hydroxyl group, Z represents a hydrogen atom, Ar′ represents a diphenylmethyl group, a pyridyl group, a partially saturated 5-membered heterocyclic group or a phenyl group, n has a value of 0 or 1, and pharmaceutically suitable acid addition salts thereof.