gamma-Glutamyltyrosine

Base Information

• Chemical Name: gamma-Glutamyltyrosine
• CAS No.: 7432-23-7
• Molecular Formula: C14H18N2O6
• Molecular Weight: 310.307
• European Community (EC) Number: 231-076-5
• DSSTox Substance ID: DTXSID00995841
• Nikkaji Number: J278.836E
• Wikidata: Q27156509
• Metabolomics Workbench ID: 41513
• Mol file: 7432-23-7.mol

Synonyms:gamma-glutamyl-L-tyrosine;gamma-glutamyltyrosine;glutyrosine

Chemical Property of gamma-Glutamyltyrosine

Chemical Property:

• Vapor Pressure: 5.2E-20mmHg at 25°C
• Melting Point: 219-221 °C
• Boiling Point: 690.4°C at 760 mmHg
• PKA: 2.22±0.10(Predicted)
• Flash Point: 371.3°C
• PSA: 149.95000
• Density: 1.414g/cm³
• LogP: 0.78740
• Storage Temp.: -15°C
• XLogP3: -3.8
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 8
• Exact Mass: 310.11648630
• Heavy Atom Count: 22
• Complexity: 406

Purity/Quality:

99%+, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC(C(=O)O)NC(=O)CCC(C(=O)O)N)O
• Isomeric SMILES: C1=CC(=CC=C1C[C@@H](C(=O)O)NC(=O)CC[C@@H](C(=O)O)N)O

Technology Process of gamma-Glutamyltyrosine

There total 3 articles about gamma-Glutamyltyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ g-L-Glutamyl-L-tyrosine (7432-23-7)

Guidance literature:

With methanol; palladium; acetic acid; Hydrogenolyse;

Reference yield:

L-tyrosine benzyl ester (42406-77-9) → g-L-Glutamyl-L-tyrosine (7432-23-7)

Guidance literature:

With dichloromethane; dicyclohexyl-carbodiimide; Hydrieren des erhaltenen Esters an Palladium in Aethanol und Erwaermen des Reaktionsprodukts mit wss. Essigsaeure;

Reference yield:

N-benzyloxycarbonyl-L-glutamic acid-5-hydrazide (4510-09-2) + L-tyrosine ethyl ester (949-67-7) → g-L-Glutamyl-L-tyrosine (7432-23-7)

Guidance literature:

With chloroform; Behandeln des erhaltenen Esters mit wss. NaOH und Hydrieren des Reaktionsprodukts an Palladium in wss. Methanol;

DOI:10.1039/jr9500001954

upstream raw materials:

N-benzyloxycarbonyl-L-glutamic acid-5-hydrazide

L-tyrosine ethyl ester

L-tyrosine benzyl ester

Downstream raw materials:

L-glutamic acid

L-tyrosine