2-(1,1-Dimethoxy-2-hydroxypropyl)-6-chlorocarbazole

Base Information

Chemical Name:2-(1,1-Dimethoxy-2-hydroxypropyl)-6-chlorocarbazole
CAS No.:114041-35-9
Molecular Formula:C₁₇H₁₈ClNO₃
Molecular Weight:319.788
Hs Code.:
UNII:LL0J6029U0
Wikidata:Q27283052
Mol file:114041-35-9.mol

Synonyms:114041-35-9;2-(1,1-Dimethoxy-2-hydroxypropyl)-6-chlorocarbazole;UNII-LL0J6029U0;1-(6-chloro-9H-carbazol-2-yl)-1,1-dimethoxypropan-2-ol;LL0J6029U0;9H-Carbazole-2-ethanol, 6-chloro-beta,beta-dimethoxy-alpha-methyl-;(+/-)-2-(1,1-Dimethoxy-2-hydroxypropyl)-6-chlorocarbazole;6-Chloro-beta,beta-dimethoxy-alpha-methyl-9H-carbazole-2-ethanol;6-Chloro-beta,beta-dimethoxy-alpha-methyl-;SCHEMBL10771543;Q27283052;6-Chloro-?,?-dimethoxy-?-methyl-9H-carbazole-2-ethanol;6-chloro-|A,|A-diemethoxy-|A-methyl-9H-carbazole-2-ethanol;6-Chloro- beta , beta -dimethoxy- alpha -methyl-9H-carbazole-2-ethanol;9H-CARBAZOLE-2-ETHANOL, 6-CHLORO-.BETA.,.BETA.-DIMETHOXY-.ALPHA.-METHYL-

Suppliers and Price of 2-(1,1-Dimethoxy-2-hydroxypropyl)-6-chlorocarbazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-β,β-dimethoxy-α-methyl-9H-carbazole-2-ethanol
10mg
$ 155.00

TRC
6-Chloro-β,β-dimethoxy-α-methyl-9H-carbazole-2-ethanol
100mg
$ 1230.00

American Custom Chemicals Corporation
6-CHLORO-BETA,BETA-DIMETHOXY-ALPHA-METHYL-9H-CARBAZOLE-2-ETHANOL 95.00%
10MG
$ 315.00

Total 3 raw suppliers

Chemical Property of 2-(1,1-Dimethoxy-2-hydroxypropyl)-6-chlorocarbazole

Chemical Property:

Vapor Pressure:2.38E-11mmHg at 25°C
Boiling Point:513°C at 760 mmHg
Flash Point:264.1°C
PSA：54.48000
Density:1.322g/cm³
LogP:3.80090
XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:319.0975211
Heavy Atom Count:22
Complexity:390

Purity/Quality:

99% ^*data from raw suppliers

6-Chloro-β,β-dimethoxy-α-methyl-9H-carbazole-2-ethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)(OC)OC)O

Technology Process of 2-(1,1-Dimethoxy-2-hydroxypropyl)-6-chlorocarbazole

There total 3 articles about 2-(1,1-Dimethoxy-2-hydroxypropyl)-6-chlorocarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.4%

: 124-41-4
sodium methylate

: 114041-34-8
2-(α-chloropropionyl)-6-chloro-9-acetylcarbazole

: 114041-35-9
2-(α,α-dimethoxy-β-hydroxypropyl)-6-chlorocarbazole

Guidance literature:: In methanol; at 42 ℃; for 4h;

Reference yield:

: 86-74-8,105184-46-1,97960-57-1
9H-carbazole

: 114041-35-9
2-(α,α-dimethoxy-β-hydroxypropyl)-6-chlorocarbazole

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) conc. H₂SO₄, 2.) AlCl₃ / 1.) CCl₄, reflux, 4 h, 2.) 50 deg C, 2.5 h

2: 1.) trichloroisocyanuric acid, 2.) HCl(g) / 1.) DMF, 40 deg C, 2 h, 2.) DMF, 40 deg C

3: 97.4 percent / methanol / 4 h / 42 °C

With hydrogenchloride; aluminium trichloride; trichloroisocyanuric acid; sulfuric acid; In methanol;

Reference yield:

: 114041-33-7
2-(α-chloropropionyl)-9-acetylcarbazole

: 114041-35-9
2-(α,α-dimethoxy-β-hydroxypropyl)-6-chlorocarbazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) trichloroisocyanuric acid, 2.) HCl(g) / 1.) DMF, 40 deg C, 2 h, 2.) DMF, 40 deg C

2: 97.4 percent / methanol / 4 h / 42 °C

With hydrogenchloride; trichloroisocyanuric acid; In methanol;