N-Biotinyl-1,6-hexanediamine

Base Information

Chemical Name:N-Biotinyl-1,6-hexanediamine
CAS No.:65953-56-2
Molecular Formula:C16H30N4O2S
Molecular Weight:342.506
Hs Code.:
DSSTox Substance ID:DTXSID30455983
Wikidata:Q82278169

Synonyms:65953-56-2;N-Biotinyl-1,6-hexanediamine;N-(6-Aminohexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-(6-aminohexyl)pentanamide;Biotinyl hexylamine;5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(6-aminohexyl)pentanamide;SCHEMBL3066083;(N-biotinyl)hexamethylenediamine;DTXSID30455983;MFCD09264744;AKOS024464471;GS-5683;(3aS,4S,6aR)-N-(6-Aminohexyl)hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;H10053;A867564

Suppliers and Price of N-Biotinyl-1,6-hexanediamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Biotinyl-1,6-hexanediamine
100mg
$ 140.00

TRC
N-Biotinyl-1,6-hexanediamine
1g
$ 1110.00

Crysdot
N-(6-Aminohexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 95+%
1g
$ 889.00

Chemenu
N-(6-Aminohexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 95%
1g
$ 839.00

Alichem
N-(6-Aminohexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
1g
$ 765.32

AK Scientific
N-(6-Aminohexyl)-5-((3as,4s,6ar)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
250mg
$ 293.00

AK Scientific
N-(6-Aminohexyl)-5-((3as,4s,6ar)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
100mg
$ 158.00

Total 20 raw suppliers

Chemical Property of N-Biotinyl-1,6-hexanediamine

Chemical Property:

Melting Point:184-186°C
Boiling Point:655.0±50.0 °C(Predicted)
PKA:13.90±0.40(Predicted)
PSA：128.53000
Density:1.116±0.06 g/cm3(Predicted)
LogP:2.85690
Storage Temp.:-20?C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:0.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:11
Exact Mass:342.20894739
Heavy Atom Count:23
Complexity:394

Purity/Quality:

97% ^*data from raw suppliers

N-Biotinyl-1,6-hexanediamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2C(C(S1)CCCCC(=O)NCCCCCCN)NC(=O)N2
Isomeric SMILES:C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCCCCCN)NC(=O)N2
Uses Intermediate in the preparation of serum biotinidase resistant Biotin derivatives used to make pretargeted diagnosis of tumors.

Technology Process of N-Biotinyl-1,6-hexanediamine

There total 12 articles about N-Biotinyl-1,6-hexanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 153162-70-0
tert-butyl (6-(5-((3aS,4S,6aR)-3a,6a-dimethyl-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)carbamate

: 65953-56-2
N-(6-aminohexyl)-5-((3aS,4S,6aR)-3a,6a-dimethyl-2-oxohexahydro-1H-thieno[3,4-d] imidazol-4-yl)pentanamide

Guidance literature:: With trifluoroacetic acid; for 0.0833333h; Sonication;
DOI:10.1021/jm800099g

Reference yield: 99.0%

: 124-09-4
1,6-Hexanediamine

: 58-85-5,22879-79-4
biotin

: 65953-56-2
N-(6-aminohexyl)-5-((3aS,4S,6aR)-3a,6a-dimethyl-2-oxohexahydro-1H-thieno[3,4-d] imidazol-4-yl)pentanamide

Guidance literature:: biotin; With di(succinimido) carbonate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 6h; Inert atmosphere;

1,6-Hexanediamine; In N,N-dimethyl-formamide; Inert atmosphere;
DOI:10.1039/b906125h