(S)-ETHYL 3-METHYL-2-((R)-5-(PERFLUOROPHENYL)-3-P-TOLYL-1,2,4-OXADIAZOL-4(5H)-YL)BUTANOATE

Base Information

Chemical Name:(S)-ETHYL 3-METHYL-2-((R)-5-(PERFLUOROPHENYL)-3-P-TOLYL-1,2,4-OXADIAZOL-4(5H)-YL)BUTANOATE
CAS No.:916676-22-7
Molecular Formula:C₂₂H₂₁F₅N₂O₃
Molecular Weight:456.412
Hs Code.:
Mol file:916676-22-7.mol

Synonyms:(S)-ETHYL 3-METHYL-2-((R)-5-(PERFLUOROPHENYL)-3-P-TOLYL-1,2,4-OXADIAZOL-4(5H)-YL)BUTANOATE

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-ETHYL 3-METHYL-2-((R)-5-(PERFLUOROPHENYL)-3-P-TOLYL-1,2,4-OXADIAZOL-4(5H)-YL)BUTANOATE

Chemical Property:

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Technology Process of (S)-ETHYL 3-METHYL-2-((R)-5-(PERFLUOROPHENYL)-3-P-TOLYL-1,2,4-OXADIAZOL-4(5H)-YL)BUTANOATE

There total 12 articles about (S)-ETHYL 3-METHYL-2-((R)-5-(PERFLUOROPHENYL)-3-P-TOLYL-1,2,4-OXADIAZOL-4(5H)-YL)BUTANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 916676-17-0
ethyl (S,E)-3-methyl-2-(perfluorobenzylideneamino)butanoate

: 36288-37-6
4-methylbenzohydroximoyl chloride

: 916676-22-7
ethyl (R)-3-methyl-2-[(R)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (S)-3-methyl-2-[(R)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (R)-3-methyl-2-[(S)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (S)-3-methyl-2-[(S)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 48h; Title compound not separated from byproducts;
DOI:10.1016/j.tet.2006.06.119

Reference yield:

: 916676-17-0
ethyl (S,E)-3-methyl-2-(perfluorobenzylideneamino)butanoate

: 36288-37-6
4-methylbenzohydroximoyl chloride

: 916676-22-7
ethyl (R)-3-methyl-2-[(R)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (S)-3-methyl-2-[(R)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (R)-3-methyl-2-[(S)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (S)-3-methyl-2-[(S)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 48h; Title compound not separated from byproducts;
DOI:10.1016/j.tet.2006.06.119

Reference yield:

: 916676-17-0
ethyl (S,E)-3-methyl-2-(perfluorobenzylideneamino)butanoate

: 36288-37-6
4-methylbenzohydroximoyl chloride

: 916676-22-7
ethyl (R)-3-methyl-2-[(R)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (S)-3-methyl-2-[(R)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (R)-3-methyl-2-[(S)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

: 916676-22-7
ethyl (S)-3-methyl-2-[(S)-5-(perfluorophenyl)-3-p-tolyl-1,2,4-oxazol-4(5H)-yl]-3-methylbutanoate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 48h; Title compound not separated from byproducts;
DOI:10.1016/j.tet.2006.06.119