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24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506

Base Information
  • Chemical Name:24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
  • CAS No.:133941-75-0
  • Molecular Formula:C56H97NO12Si2
  • Molecular Weight:1032.56
  • Hs Code.:
  • Mol file:133941-75-0.mol
24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506

Synonyms:133941-75-0;24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506

Suppliers and Price of 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
  • 5mg
  • $ 175.00
  • Biosynth Carbosynth
  • 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
  • 2 mg
  • $ 139.90
  • Biosynth Carbosynth
  • 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
  • 50 mg
  • $ 1529.00
  • Biosynth Carbosynth
  • 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
  • 25 mg
  • $ 841.00
  • Biosynth Carbosynth
  • 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
  • 10 mg
  • $ 462.50
  • Biosynth Carbosynth
  • 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
  • 5 mg
  • $ 254.40
Total 15 raw suppliers
Chemical Property of 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
Chemical Property:
  • Boiling Point:899.3±75.0 °C(Predicted) 
  • PKA:9.96±0.70(Predicted) 
  • PSA:156.36000 
  • Density:1.08±0.1 g/cm3(Predicted) 
  • LogP:10.63590 
  • Storage Temp.:-20°C Freezer 
  • Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly) 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:12
  • Rotatable Bond Count:13
  • Exact Mass:1031.65493060
  • Heavy Atom Count:71
  • Complexity:1900
Purity/Quality:

99% *data from raw suppliers

24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506 *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O[Si](C)(C)C(C)(C)C)C)C(=CC4CCC(C(C4)OC)O[Si](C)(C)C(C)(C)C)C)O)C)OC)OC
  • Isomeric SMILES:C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\C)CC=C)O[Si](C)(C)C(C)(C)C)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O[Si](C)(C)C(C)(C)C)/C)O)C)OC)OC
  • Uses Protected form of FK-506 (Tacrolimus)
Technology Process of 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506

There total 3 articles about 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With 1H-imidazole; In N,N-dimethyl-formamide;
DOI:10.1002/jlcr.558
Guidance literature:
With 2,6-dimethylpyridine; In dichloromethane; at 0 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ja206339s
Guidance literature:
With epichlorohydrin; In 1,2-dichloro-benzene; at 140 ℃; for 0.05h;
DOI:10.1016/S0040-4039(02)02705-3
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