N-(3,5-DibroMo-2-pyridyl)thiourea, 97%

Base Information

• Chemical Name: N-(3,5-DibroMo-2-pyridyl)thiourea, 97%
• CAS No.: 31545-35-4
• Molecular Formula: C₆H₅Br₂N₃S
• Molecular Weight: 311
• Hs Code.: 2933399090
• Mol file: 31545-35-4.mol

Synonyms:N-(3,5-DibroMo-2-pyridyl)thiourea, 97%;Thiourea, N-(3,5-dibroMo-2-pyridinyl)-;1-(3,5-Dibromopyridin-2-yl)thiourea

Chemical Property of N-(3,5-DibroMo-2-pyridyl)thiourea, 97%

Chemical Property:

• Melting Point: 233-237℃
• Flash Point: >110°(230°F)
• PSA: 83.03000
• LogP: 3.03540

Purity/Quality:

99.3% ^*data from raw suppliers

(3,5-Dibromo-pyridin-2-yl)-thiourea 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(3,5-DibroMo-2-pyridyl)thiourea, 97%

There total 4 articles about N-(3,5-DibroMo-2-pyridyl)thiourea, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-[(3,5-dibromopyridin-2-yl)carbamothioyl]benzamide (31430-58-7) → 1-(3,5-dibromopyridin-2-yl)thiourea (31545-35-4)

Guidance literature:

With water; sodium hydroxide; In methanol; for 1h; Reflux;

Reference yield: 45.36%

2-amino-3,5-dibromopyridine (35486-42-1) + thiocarboxamide (115-08-2) → 1-(3,5-dibromopyridin-2-yl)thiourea (31545-35-4)

Guidance literature:

2-amino-3,5-dibromopyridine; thiocarboxamide; With benzoyl chloride; In tetrahydrofuran; at 80 ℃; for 12h;

With sodium hydroxide; In methanol; water; Temperature; Reflux;

Reference yield:

2-amino-3,5-dibromopyridine (35486-42-1) → 1-(3,5-dibromopyridin-2-yl)thiourea (31545-35-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 18 h / 20 °C

2: water; sodium hydroxide / methanol / 1 h / Reflux

With water; sodium hydroxide; In methanol; acetone;

upstream raw materials:

2-amino-3,5-dibromopyridine

N-[(3,5-dibromopyridin-2-yl)carbamothioyl]benzamide

thiocarboxamide

Downstream raw materials:

6-bromo-2-chlorothiazolo[4,5-b]pyridine

2-amino-6-bromo[1,3]thiazolo[4,5-b]pyridine

6-bromo[1,3]thiazolo[4,5-b]pyridine

methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

Refernces

• 1、 -. "ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON VASCULAR ENDOTHELIAL LIPASE". . . Retrieved 2011/08/08.