methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

Base Information

Chemical Name:methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester
CAS No.:2104019-86-3
Molecular Formula:C₈H₆N₂O₂S
Molecular Weight:194.214
Hs Code.:

Synonyms:

Suppliers and Price of methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 5 raw suppliers

Chemical Property of methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

There total 4 articles about methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.3%

: 67-56-1
methanol

: 201230-82-2
carbon monoxide

: 1264193-12-5
6-bromo[1,3]thiazolo[4,5-b]pyridine

: 2104019-86-3
methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

Guidance literature:: With pyridine; bis-triphenylphosphine-palladium(II) chloride; at 115 ℃; for 12h; under 75.0075 Torr; Temperature;

Reference yield:

: 31545-35-4
1-(3,5-dibromopyridin-2-yl)thiourea

: 2104019-86-3
methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride / 5 h / 70 °C

2: isopentyl nitrite / tetrahydrofuran / 11 h / Reflux

3: pyridine; bis-triphenylphosphine-palladium(II) chloride / 12 h / 115 °C / 75.01 Torr

With pyridine; bis-triphenylphosphine-palladium(II) chloride; sodium hydride; isopentyl nitrite; In tetrahydrofuran;

Reference yield:

: 857970-06-0
2-amino-6-bromo[1,3]thiazolo[4,5-b]pyridine

: 2104019-86-3
methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: isopentyl nitrite / tetrahydrofuran / 11 h / Reflux

2: pyridine; bis-triphenylphosphine-palladium(II) chloride / 12 h / 115 °C / 75.01 Torr

With pyridine; bis-triphenylphosphine-palladium(II) chloride; isopentyl nitrite; In tetrahydrofuran;