ethyl 3-(tert-butoxycarbonylaMino)-2,2-diMethylpropanoate

Base Information

Chemical Name:ethyl 3-(tert-butoxycarbonylaMino)-2,2-diMethylpropanoate
CAS No.:204514-14-7
Molecular Formula:C12H23NO4
Molecular Weight:245.31532
Hs Code.:
Mol file:204514-14-7.mol

Synonyms:ethyl 3-(tert-butoxycarbonylaMino)-2,2-diMethylpropanoate;3-[[(1,1-dimethylethoxy)carbonyl]amino]-2,2-dimethylPropanoic acid ethyl ester

Suppliers and Price of ethyl 3-(tert-butoxycarbonylaMino)-2,2-diMethylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl3-((tert-butoxycarbonyl)amino)-2,2-dimethylpropanoate 97%
5g
$ 953.00

AK Scientific
Ethyl3-((tert-butoxycarbonyl)amino)-2,2-dimethylpropanoate
1g
$ 1275.00

Total 3 raw suppliers

Chemical Property of ethyl 3-(tert-butoxycarbonylaMino)-2,2-diMethylpropanoate

Chemical Property:

Boiling Point:329.6±25.0 °C(Predicted)
PKA:12.13±0.46(Predicted)
PSA：68.12000
Density:1.011±0.06 g/cm3(Predicted)
LogP:2.30480

Purity/Quality:

97% ^*data from raw suppliers

Ethyl3-((tert-butoxycarbonyl)amino)-2,2-dimethylpropanoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 3-(tert-butoxycarbonylaMino)-2,2-diMethylpropanoate

There total 6 articles about ethyl 3-(tert-butoxycarbonylaMino)-2,2-diMethylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 80253-38-9
3-amino-2,2-dimethylpropionic acid ethyl ester hydrochloride

: 204514-14-7
ethyl 2,2-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Guidance literature:: With triethylamine; pentane; In dichloromethane; at 0 - 23 ℃; for 20h;

Reference yield: 93.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 3-((tert-butoxycarbonyl)(methyl)amino)-2,2-dimethylpropanoic acid

: 204514-14-7
ethyl 2,2-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

: 1572-98-1
2-cyano-2-methyl-propionic acid ethyl ester

: 204514-14-7
ethyl 2,2-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 5 percent Rh/Al₂O₃

With hydrogen; Rh/Al₂O₃; 1: Reduction / 2: Acylation;
DOI:10.1016/S0960-894X(00)00174-8