(3-Glycidoxypropyl)bis(trimethylsiloxy)methylsilane

Base Information

• Chemical Name: (3-Glycidoxypropyl)bis(trimethylsiloxy)methylsilane
• CAS No.: 7422-52-8
• Molecular Formula: C13H32O4Si3
• Molecular Weight: 336.651
• Hs Code.: 2934999090
• European Community (EC) Number: 231-045-6
• DSSTox Substance ID: DTXSID20884384
• Nikkaji Number: J278.825J
• Mol file: 7422-52-8.mol

Synonyms:7422-52-8;(3-Glycidoxypropyl)bis(trimethylsiloxy)methylsilane;1,1,1,3,5,5,5-Heptamethyl-3-(3-glycidyloxypropyl)trisiloxane;trimethyl-[methyl-[3-(oxiran-2-ylmethoxy)propyl]-trimethylsilyloxysilyl]oxysilane;C13H32O4Si3;EINECS 231-045-6;Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-(3-(2-oxiranylmethoxy)propyl)-;Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-(3-(oxiranylmethoxy)propyl)-;Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-[3-(oxiranylmethoxy)propyl]-;1,1,1,3,5,5,5-Heptamethyl-3-(3-(oxiranylmethoxy)propyl)trisiloxane;1,1,1,3,5,5,5-heptamethyl-3-[3-(oxiranylmethoxy)propyl]trisiloxane;Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-[3-(2-oxiranylmethoxy)propyl]-;SCHEMBL150315;DTXSID20884384;C13-H32-O4-Si3;MFCD29050194;AKOS025295685;CS-0199225;H1266;D91022;3-(Bis(trimethylsiloxy)methyl)-propyl glycidyl ether;3-[Bis(trimethylsiloxy)methyl]propyl glycidyl ether;[3-(glycidoxypropyl]-1,1,1,3,5,5,5-heptamethyltrisiloxane);3-[3-(2,3-epoxypropoxy)propyl]-1,1,1,3,5,5,5-heptamethyltrisiloxane;3-[3-(Glycidyloxy)propyl]-1,1,1,3,5,5,5-heptamethylpentanetrisiloxane;Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-[3-(oxiranyl-methoxy)propyl]-

Chemical Property of (3-Glycidoxypropyl)bis(trimethylsiloxy)methylsilane

Chemical Property:

• Vapor Pressure: 0.000674mmHg at 25°C
• Refractive Index: 1.4206
• Boiling Point: 318.4 °C at 760 mmHg
• Flash Point: 125.1 °C
• PSA: 40.22000
• Density: 0.943 g/cm³
• LogP: 3.17620
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 10
• Exact Mass: 336.16083910
• Heavy Atom Count: 20
• Complexity: 283

Purity/Quality:

98% ^*data from raw suppliers

(3-Glycidoxypropyl)bis(trimethylsiloxy)methylsilane ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)O[Si](C)(CCCOCC1CO1)O[Si](C)(C)C

Technology Process of (3-Glycidoxypropyl)bis(trimethylsiloxy)methylsilane

There total 6 articles about (3-Glycidoxypropyl)bis(trimethylsiloxy)methylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Allyl glycidyl ether (106-92-3,25639-25-2,90907-93-0) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 1-bis(trimethylsilyloxy)methylsilyl-3-(oxiran-2-ylmethoxy)-1-propanol (7422-52-8)

Guidance literature:

With bis(1-butyl-4-methylpyridinium) hexachloroplatinate(IV); Reagent/catalyst;

DOI:10.1016/j.jcat.2019.05.005

Reference yield:

Allyl glycidyl ether (106-92-3,25639-25-2,90907-93-0) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + carbon dioxide (124-38-9,18923-20-1) → 1-bis(trimethylsilyloxy)methylsilyl-3-(oxiran-2-ylmethoxy)-1-propanol (7422-52-8)

Guidance literature:

With silica supproted Rh-NEt₂; In neat (no solvent); at 80 ℃; for 24h; under 760.051 Torr;

DOI:10.1021/acs.orglett.9b03602

Reference yield:

Allyl glycidyl ether (106-92-3,25639-25-2,90907-93-0) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 1-bis(trimethylsilyloxy)methylsilyl-3-(oxiran-2-ylmethoxy)-1-propanol (7422-52-8) + C13H30O4Si3

Guidance literature:

With (^TFAPDI)Co(2-ethylhexanoate)₂; at 20 ℃; for 1h; Reagent/catalyst; Overall yield = 96 %; Overall yield = 289 mg; Inert atmosphere; Sealed tube;

upstream raw materials:

Allyl glycidyl ether

1,1,1,3,5,5,5-heptamethyltrisiloxan

carbon dioxide

Downstream raw materials:

(3-methacryloxy-2-hydroxypropoxy)propyl-bis(trimethylsiloxy)methylsilane

C₁₃H₃₄O₅Si₃

(2-methacryloxy-3-hydroxypropyloxy)propylbis(trimethylsiloxy)methylsilane