1,1,1,3,5,5,5-Heptamethyltrisiloxane

Base Information

• Chemical Name: 1,1,1,3,5,5,5-Heptamethyltrisiloxane
• CAS No.: 1873-88-7
• Molecular Formula: C7H22O2Si3
• Molecular Weight: 222.507
• Hs Code.: 29319090
• European Community (EC) Number: 217-496-1
• UNII: RVY9659R8C
• DSSTox Substance ID: DTXSID1038795
• ChEMBL ID: CHEMBL3988892
• Mol file: 1873-88-7.mol

Synonyms:1,1,1,3,5,5,5-Heptamethyltrisiloxane;1873-88-7;Bis(trimethylsiloxy)methylsilane;Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-;methyl-bis(trimethylsilyloxy)silicon;heptamethyl trisiloxane;UNII-RVY9659R8C;RVY9659R8C;DTXSID1038795;Methylbis(trimethylsilyloxy)silane;EINECS 217-496-1;EC 217-496-1;26403-67-8;Methicone (20 CST);DSSTox_CID_18795;DSSTox_RID_82383;DSSTox_GSID_47501;Hptso//Heptamethyltrisiloxane;SCHEMBL41518;di(trimethylsiloxy)methylsilane;Kf 99;UNII-6777U11MKT;CHEMBL3988892;DTXCID9018795;SIB-1844;Tox21_301069;Tox21_302481;MFCD00048000;AKOS015840182;CS-W014234;HEPTAMETHYL TRISILOXANE [USP-RS];NCGC00248277-01;NCGC00254970-01;NCGC00256718-01;BS-15733;CAS-1873-88-7;CAS-9004-73-3;FT-0626916;H1267;Trisiloxano, 1,1,1,3,5,5,5-heptametil-;S09300;Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-,

Chemical Property of 1,1,1,3,5,5,5-Heptamethyltrisiloxane

Chemical Property:

• Appearance/Colour: Colourless liquid
• Vapor Pressure: 8.5hPa at 25℃
• Melting Point: <0 °C
• Refractive Index: n20/D 1.382(lit.)
• Boiling Point: 163.8 °C at 760 mmHg
• Flash Point: 52.8 °C
• PSA: 18.46000
• Density: 0.819 g/cm³
• LogP: 2.53970
• Storage Temp.: 15-25°C
• Water Solubility.: Miscible with acetone, ethanol, diethyl ether. Insoluble in water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 221.08493451
• Heavy Atom Count: 12
• Complexity: 121

Purity/Quality:

99.5%min ^*data from raw suppliers

Heptamethyl trisiloxane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](O[Si](C)(C)C)O[Si](C)(C)C
• Uses: Heptamethyltrisiloxane is used to catalyze reduction reactions in organic syntheses. 1,1,1,3,5,5,5-Heptamethyltrisiloxane is a Basic material for synthetic polyalkyleneoxide modified heptamethyltrisiloxane which is a kind of specific structure surfactant for pesticide additives, coating additives, etc. Bis(trimethylsiloxy)methylsilane is an important raw material and intermediate used in organic synthesis, pharmaceutical and dyestuff. 1,1,1,3,5,5,5-Heptamethyltrisiloxane can be used for the aromatic C-H silylation of arenes in the presence of a platinum complex catalyst.It can also be used as a reagent to synthesize: 3-Octyl-1,1,1,3,5,5,5-heptamethyltrisiloxane, an agricultural adjuvant and sensory performance enhancer used in cosmetic formulations.Isoindigo-based conjugated polymer with siloxane-terminated solubilizing group.Monosiloxy esters with a variety of acids.
• Description: Bis (trimethylsiloxy) methylsilane acts as an important raw material and intermediate used in organic synthesis, pharmaceutical and dyestuff. For example, it can be used for the platinum-catalyzed aromatic C-H silylation of arenes. It can also be used for the silylation of aryl iodides.

Technology Process of 1,1,1,3,5,5,5-Heptamethyltrisiloxane

There total 15 articles about 1,1,1,3,5,5,5-Heptamethyltrisiloxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

Dichloromethylsilane (75-54-7) + chloro-trimethyl-silane (75-77-4) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Guidance literature:

With Methamphetamin; In diethyl ether; for 1h;

Reference yield: 59.0%

Dichloromethylsilane (75-54-7) + sodium trimethylsilanolate (18027-10-6) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Guidance literature:

In diethyl ether; for 10h; Heating;

DOI:10.1007/BF00949632

Reference yield: 34.0%

Dichloromethylsilane (75-54-7) + Trimethylsilanol (1066-40-6) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Guidance literature:

With pyridine; In hexane; at -30 - 20 ℃; for 16h;

DOI:10.1007/s11172-016-1449-1

upstream raw materials:

Dichloromethylsilane

chloro-trimethyl-silane

Hexamethyldisiloxane

1,3,5,7,9-pentamethylcyclopentasiloxane

Downstream raw materials:

1,1,1,3,5,5,5-heptamethyl-3-phenethyltrisiloxane

isonicotinic acid 2-methoxy-4-[3-(bis(trimethylsiloxy)methylsilyl)propyl]phenyl ester

3-chloro-1,1,1,3,5,5,5-heptamethyltrisiloxane

3-propenyl-1,1,1,3,5,5,5-heptamethyltrisiloxane

Refernces

• 1、 -. "Method for preparing 1, 1, 1, 3, 5, 5, 5-heptamethyltrisiloxane". Paragraph 0009; 0010. . Retrieved 2016/11/17.
• 2、 Trofimov,Skvortsov,Pashnova,Skvortsov. "Hydrosilation of endo-cis-5-Norbornene-2,3-dicarboxylic Anhydride". . p. 572 - 577. Retrieved 2007/10/03.