(5S)-5-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethylsilyl)oxy]Methyl]-2-Pyrrolidinone

Base Information

Chemical Name:(5S)-5-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethylsilyl)oxy]Methyl]-2-Pyrrolidinone
CAS No.:1092807-29-8
Molecular Formula:C24H21F12NO2Si
Molecular Weight:611.4953784
Hs Code.:
Mol file:1092807-29-8.mol

Synonyms:(5S)-5-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethylsilyl)oxy]Methyl]-2-Pyrrolidinone

Suppliers and Price of (5S)-5-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethylsilyl)oxy]Methyl]-2-Pyrrolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (5S)-5-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethylsilyl)oxy]Methyl]-2-Pyrrolidinone

Chemical Property:

Melting Point:129 - 130 °C
PSA：38.33000
LogP:8.46430

Purity/Quality:: >95%,>98%e.e. ^*data from raw suppliers

Safty Information:

Pictogram(s):
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Technology Process of (5S)-5-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethylsilyl)oxy]Methyl]-2-Pyrrolidinone

There total 1 articles about (5S)-5-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethylsilyl)oxy]Methyl]-2-Pyrrolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 27607-77-8
trimethylsilyl trifluoromethanesulfonate

: 1092807-24-3
(S)-5-{bis[3,5-bis(trifluoromethyl)phenyl](hydroxy)methyl}pyrrolidin-2-one

: 1092807-29-8
(S)-5-{bis[3,5-bis(trifluoromethyl)phenyl](trimethylsiloxy)methyl}pyrrolidin-2-one

Guidance literature:: With triethylamine; Inert atmosphere;
DOI:10.1055/s-2008-1067216

Reference yield: 82.0%

: 1092807-29-8
(S)-5-{bis[3,5-bis(trifluoromethyl)phenyl](trimethylsiloxy)methyl}pyrrolidin-2-one

: 420-37-1
trimethoxonium tetrafluoroborate

: 3471-32-7
4-Methoxyphenylhydrazine

: 1092807-37-8
(S)-5-{bis[3,5-bis(trifluoromethyl)phenyl](hydroxy)methyl}-2-(4-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[2,1-c]-1,2,4-triazol-2-ium tetrafluoroborate

Guidance literature:: (S)-5-{bis[3,5-bis(trifluoromethyl)phenyl](trimethylsiloxy)methyl}pyrrolidin-2-one; trimethoxonium tetrafluoroborate; Inert atmosphere;

4-Methoxyphenylhydrazine; Inert atmosphere;

With trimethyl orthoformate; In methanol; at 110 ℃; for 15h; Inert atmosphere;
DOI:10.1055/s-2008-1067216