3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid

Base Information

Chemical Name:3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid
CAS No.:1736-20-5
Molecular Formula:C11H8FNO3
Molecular Weight:221.188
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00424363
Wikidata:Q82236902
Mol file:1736-20-5.mol

Synonyms:1736-20-5;3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid;3-(2-fluorophenyl)-5-methylisoxazole-4-carboxylic acid;3-(2-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylic acid;SCHEMBL3826089;DTXSID00424363;ZSDKQOQGZGDHNC-UHFFFAOYSA-N;MFCD07186382;AKOS000264900;BB 0253711;CS-0214852;EN300-199226;4-Carboxy-5-methyl-3-(2-fluorophenyl)isoxazole;3-(2-fluorophenyl)-5-methylisoxazole-4-carboxylicacid;3-(2-Fluorophenyl)-5-methyl-isoxazole-4-carboxylic acid;3-(2-fluorophenyl)-5-methylisoxazol-4-carboxylic acid;Z1201049403

Suppliers and Price of 3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(2-fluorophenyl)-5-methylisoxazole-4-carboxylicAcid
10mg
$ 45.00

Matrix Scientific
3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid
1g
$ 700.00

Matrix Scientific
3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid
500mg
$ 455.00

Heterocyclics
3-(2-Fluorophenyl)-5-methyl-4-isoxazolecarboxylicacid
5g
$ 848.00

Heterocyclics
3-(2-Fluorophenyl)-5-methyl-4-isoxazolecarboxylicacid
250mg
$ 270.00

Heterocyclics
3-(2-Fluorophenyl)-5-methyl-4-isoxazolecarboxylicacid
1g
$ 675.00

Crysdot
3-(2-Fluorophenyl)-5-methylisoxazole-4-carboxylicacid 95+%
5g
$ 772.00

Chemenu
3-(2-Fluorophenyl)-5-methylisoxazole-4-carboxylicacid 95%
5g
$ 729.00

American Custom Chemicals Corporation
3-(2-FLUORO-PHENYL)-5-METHYL-ISOXAZOLE-4-CARBOXYLIC ACID 95.00%
500MG
$ 777.32

AK Scientific
3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylicacid
10g
$ 2062.00

Total 6 raw suppliers

Chemical Property of 3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid

Chemical Property:

PSA：63.33000
LogP:2.48730
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:221.04882128
Heavy Atom Count:16
Complexity:274

Purity/Quality:

98%min ^*data from raw suppliers

3-(2-fluorophenyl)-5-methylisoxazole-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=NO1)C2=CC=CC=C2F)C(=O)O

Technology Process of 3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid

There total 6 articles about 3-(2-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1960-93-6
methyl-3-(2-fluorophenyl)-5-methylisoxazol-4-carboxylate

: 1736-20-5
3-(2-fluorophenyl)-5-methylisoxazole-4-carboxylic acid

Guidance literature:: methyl-3-(2-fluorophenyl)-5-methylisoxazol-4-carboxylate; With sodium hydroxide; In methanol; water; at 50 ℃; for 19h;

With hydrogenchloride; In methanol; water; pH=< 3;

Reference yield:

: 39502-43-7
2-fluoro-N-hydroxybenzenecarboxymidoyl chloride

: 34284-28-1
sodium methyl acetoacetate

: 1736-20-5
3-(2-fluorophenyl)-5-methylisoxazole-4-carboxylic acid

Guidance literature:: 2-fluoro-N-hydroxybenzenecarboxymidoyl chloride; sodium methyl acetoacetate; In methanol; at 20 - 60 ℃; for 1h;

With sodium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 2h;

With hydrogenchloride; In water; toluene;