3-iodo-2-Methyl-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:3-iodo-2-Methyl-1H-pyrrolo[2,3-b]pyridine
CAS No.:1256964-50-7
Molecular Formula:C8H7IN2
Molecular Weight:258.061
Hs Code.:
Mol file:1256964-50-7.mol

Synonyms:3-iodo-2-Methyl-1H-pyrrolo[2,3-b]pyridine;3-Iodo-2-Methyl-7-azaindole

Suppliers and Price of 3-iodo-2-Methyl-1H-pyrrolo[2,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Iodo-2-methyl-1H-pyrrolo[2,3-B]pyridine
5mg
$ 45.00

SynQuest Laboratories
3-Iodo-2-methyl-7-azaindole
250 mg
$ 340.00

Matrix Scientific
3-Iodo-2-methyl-7-azaindole
1g
$ 1286.00

Chemenu
3-iodo-2-methyl-1H-pyrrolo[2,3-b]pyridine 95%+
1g
$ 724.00

Chemenu
3-iodo-2-methyl-1H-pyrrolo[2,3-b]pyridine 95%+
5g
$ 2381.00

Chemenu
3-iodo-2-methyl-1H-pyrrolo[2,3-b]pyridine 95%+
250mg
$ 255.00

Alichem
3-Iodo-2-methyl-1H-pyrrolo[2,3-b]pyridine
1g
$ 602.08

Alichem
3-Iodo-2-methyl-1H-pyrrolo[2,3-b]pyridine
5g
$ 1643.00

Abosyn
3-iodo-2-methyl-1H-pyrrolo[2,3-b]pyridine 95%-98%
1g
$ 635.00

Total 16 raw suppliers

Chemical Property of 3-iodo-2-Methyl-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

PSA：28.68000
LogP:2.47590
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

99%, ^*data from raw suppliers

3-Iodo-2-methyl-1H-pyrrolo[2,3-B]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-iodo-2-Methyl-1H-pyrrolo[2,3-b]pyridine

There total 2 articles about 3-iodo-2-Methyl-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 23612-48-8
2-methyl-1H-pyrrolo[2,3-b]pyridine

: 1256964-50-7
3-iodo-2-methylpyrrolo[2,3-b]pyridine

Guidance literature:: With iodine; potassium hydroxide; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1039/c1ob05586k

Reference yield: 70.0%

: 943324-07-0
3-Iodo-2-methyl-1-(phenylsulfonyl)pyrrolo[2,3-b]pyridine

: 1256964-50-7
3-iodo-2-methylpyrrolo[2,3-b]pyridine

Guidance literature:: With water; potassium carbonate; In methanol; for 10h; Inert atmosphere; Reflux;
DOI:10.1002/ejoc.201000599

Reference yield:

: 1256964-50-7
3-iodo-2-methylpyrrolo[2,3-b]pyridine

: 1375278-66-2
(S)-N-(benzo[d][1,3]dioxol-5-yl)-N-methyl-2-(2-(2-methyl-3-vinyl-1H-pyrrolo[2,3-b]pyridin-1-yl)acetamido)-3-phenylpropanamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / mineral oil / 0.33 h

1.2: 0.5 h / 0 °C

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / Inert atmosphere; Reflux

3.1: water; sodium hydroxide / methanol / 3 h / 20 °C

4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Inert atmosphere

With water; sodium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;