1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid

Base Information

Chemical Name:1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid
CAS No.:177409-39-1
Molecular Formula:C5H5N3O4
Molecular Weight:171.112
Hs Code.:2933199090
European Community (EC) Number:832-670-2
Mol file:177409-39-1.mol

Synonyms:1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid;177409-39-1;2-methyl-5-nitropyrazole-3-carboxylic acid;MFCD06805246;1-methyl-3-nitropyrazole-5-carboxylic acid;SCHEMBL2119388;ZTTJIDURGGLBHQ-UHFFFAOYSA-N;AKOS000308856;LS-05951;2-Methyl-5-nitro-pyrazole-3-carboxylic acid;CS-0217915;EN300-92745;1-methyl-3-nitro-1H-pyrazole-5-carboxylicacid

Suppliers and Price of 1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Methyl-3-nitro-1H-pyrazole-5-carboxylic acid
1g
$ 420.00

Matrix Scientific
1-Methyl-3-nitro-1H-pyrazole-5-carboxylic acid
500mg
$ 336.00

Crysdot
1-Methyl-3-nitro-1H-pyrazole-5-carboxylicacid 95+%
5g
$ 904.00

Crysdot
1-Methyl-3-nitro-1H-pyrazole-5-carboxylicacid 95+%
1g
$ 320.00

Chemenu
1-Methyl-3-nitro-1H-pyrazole-5-carboxylicacid 95%
1g
$ 302.00

Chemenu
1-Methyl-3-nitro-1H-pyrazole-5-carboxylicacid 95%
5g
$ 853.00

AK Scientific
1-Methyl-3-nitro-1H-pyrazole-5-carboxylicacid
1g
$ 542.00

AK Scientific
1-Methyl-3-nitro-1H-pyrazole-5-carboxylicacid
500mg
$ 448.00

Total 5 raw suppliers

Chemical Property of 1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid

Chemical Property:

Boiling Point:399.0±27.0 °C(Predicted)
PKA:2?+-.0.21(Predicted)
PSA：100.94000
Density:1.72±0.1 g/cm3(Predicted)
LogP:0.54970
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:171.02800565
Heavy Atom Count:12
Complexity:213

Purity/Quality:

98%min ^*data from raw suppliers

1-Methyl-3-nitro-1H-pyrazole-5-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C(=CC(=N1)[N+](=O)[O-])C(=O)O

Technology Process of 1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid

There total 2 articles about 1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 177409-38-0
2-methyl-5-nitro-2H-pyrazole-3-carboxylic acid methyl ester

: 177409-39-1
1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid

Guidance literature:: With potassium hydroxide; In 1,4-dioxane; for 2h; Ambient temperature;
DOI:10.1016/S0968-0896(98)00205-3

Reference yield:

: 89088-56-2
methyl 1-methyl-3-aminopyrazole-5-carboxylate

: 177409-38-0
2-methyl-5-nitro-2H-pyrazole-3-carboxylic acid methyl ester

: 177409-39-1
1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid

Guidance literature:: With sodium hydroxide; 3-chloro-benzenecarboperoxoic acid; In chloroform;

Reference yield: 42.0%

: 1318757-72-0
tert-butyl [2-(3-chloro-5-fluorobenzyl)-4-methyl-1,3-thiazol-5-yl]carbamate

: 177409-39-1
1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid

: 1318756-47-6
N-[2-(3-chloro-5-fluorobenzyl)-4-methyl-1,3-thiazol-5-yl]-1-methyl-3-nitro-1H-pyrazole-5-carboxamide

Guidance literature:: tert-butyl [2-(3-chloro-5-fluorobenzyl)-4-methyl-1,3-thiazol-5-yl]carbamate; With hydrogenchloride; In ethanol; water; at 50 ℃; for 1.5h;

With sodium hydrogencarbonate; sodium hydroxide; In ethanol; water; at 0 ℃; pH=10 - 11;

1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl acetamide; at 60 ℃; for 4h;