Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-

Base Information

Chemical Name:Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-
CAS No.:1403257-81-7
Molecular Formula:C15H20BrNO3
Molecular Weight:342.233
Hs Code.:
Mol file:1403257-81-7.mol

Synonyms:Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-;5-bromo-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzoic acid

Suppliers and Price of Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-bromo-3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-2-methyl-Benzoicacid
10mg
$ 65.00

ChemScene
Benzoicacid,5-bromo-3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-2-methyl-
1g
$ 850.00

Total 6 raw suppliers

Chemical Property of Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-

Chemical Property:

PSA：49.77000
LogP:3.46100

Purity/Quality:

97% ^*data from raw suppliers

5-bromo-3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-2-methyl-Benzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-

There total 11 articles about Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1403257-79-3
2-methyl-3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-5-bromobenzoic acid methyl ester

: 1403257-81-7
5-bromo-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methyl benzoic acid

Guidance literature:: 2-methyl-3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-5-bromobenzoic acid methyl ester; With water; sodium hydroxide; In ethanol; at 60 ℃; for 1h;

With hydrogenchloride; In water; pH=7;

With citric acid; In water; pH=5 - 6; Product distribution / selectivity;

Reference yield:

: 1000342-11-9
2-methyl-3-amino-5-bromobenzoic acid methyl ester

: 1403257-81-7
5-bromo-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methyl benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / 1,1-dichloroethane / 0.25 h / 20 °C

1.2: 0 - 20 °C

2.1: acetic acid / 1,1-dichloroethane / 0.33 h / 20 °C

2.2: 2 h / 0 - 20 °C

3.1: sodium hydroxide; water / ethanol / 1 h / 60 °C

3.2: pH 7

3.3: pH 5 - 6

With water; acetic acid; sodium hydroxide; In 1,1-dichloroethane; ethanol;

Reference yield:

: 1403257-49-7
2-methyl-3[(tetrahydro-2H-pyran-4-yl)amino]-5-bromobenzoic acid methyl ester

: 1403257-81-7
5-bromo-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methyl benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / 1,1-dichloroethane / 0.33 h / 20 °C

1.2: 2 h / 0 - 20 °C

2.1: sodium hydroxide; water / ethanol / 1 h / 60 °C

2.2: pH 7

2.3: pH 5 - 6

With water; acetic acid; sodium hydroxide; In 1,1-dichloroethane; ethanol;