BenzaMide, 5-broMo-N-[(1,2-dihydro-4,6-diMethyl-2-oxo-3-pyridinyl)Methyl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-

Base Information

Chemical Name:BenzaMide, 5-broMo-N-[(1,2-dihydro-4,6-diMethyl-2-oxo-3-pyridinyl)Methyl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-
CAS No.:1403257-80-6
Molecular Formula:C23H30BrN3O3
Molecular Weight:476.413
Hs Code.:
Mol file:1403257-80-6.mol

Synonyms:BenzaMide, 5-broMo-N-[(1,2-dihydro-4,6-diMethyl-2-oxo-3-pyridinyl)Methyl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-;5-bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide

Suppliers and Price of BenzaMide, 5-broMo-N-[(1,2-dihydro-4,6-diMethyl-2-oxo-3-pyridinyl)Methyl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide
100mg
$ 330.00

Ambeed
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide 98%(contains2-3%DCM)
1g
$ 335.00

Ambeed
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide 98%(contains2-3%DCM)
250mg
$ 132.00

Ambeed
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide 98%(contains2-3%DCM)
100mg
$ 91.00

Total 6 raw suppliers

Chemical Property of BenzaMide, 5-broMo-N-[(1,2-dihydro-4,6-diMethyl-2-oxo-3-pyridinyl)Methyl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-

Chemical Property:

Boiling Point:642.2±55.0 °C(Predicted)
PKA:11.88±0.10(Predicted)
PSA：74.43000
Density:1.302±0.06 g/cm3(Predicted)
LogP:4.38880
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of BenzaMide, 5-broMo-N-[(1,2-dihydro-4,6-diMethyl-2-oxo-3-pyridinyl)Methyl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-

There total 15 articles about BenzaMide, 5-broMo-N-[(1,2-dihydro-4,6-diMethyl-2-oxo-3-pyridinyl)Methyl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 771579-27-2
3-(aminomethyl)-4,6-dimethyl-1,2-dihydropyridin-2-one

: 1403257-81-7
5-bromo-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methyl benzoic acid

: 1403257-80-6
5-bromo-N-((4, 6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl) amino)-2-methylbenzamide

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dimethyl sulfoxide; at 20 ℃;

Reference yield:

: 1000342-11-9
2-methyl-3-amino-5-bromobenzoic acid methyl ester

: 1403257-80-6
5-bromo-N-((4, 6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl) amino)-2-methylbenzamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid / 1,2-dichloro-ethane / 0.08 h / Inert atmosphere

1.2: 64 h

2.1: acetic acid / 1,2-dichloro-ethane / 0.08 h / Inert atmosphere

2.2: 22 h / 20 °C

3.1: sodium hydroxide; water / ethanol / 1 h / 60 °C

3.2: pH 4 - 6

4.1: triethylamine / dimethyl sulfoxide / 0.25 h / 20 °C

With water; acetic acid; triethylamine; sodium hydroxide; In ethanol; dimethyl sulfoxide; 1,2-dichloro-ethane;

Reference yield:

: 1403257-49-7
2-methyl-3[(tetrahydro-2H-pyran-4-yl)amino]-5-bromobenzoic acid methyl ester

: 1403257-80-6
5-bromo-N-((4, 6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl) amino)-2-methylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / 1,2-dichloro-ethane / 0.08 h / Inert atmosphere

1.2: 22 h / 20 °C

2.1: sodium hydroxide; water / ethanol / 1 h / 60 °C

2.2: pH 4 - 6

3.1: triethylamine / dimethyl sulfoxide / 0.25 h / 20 °C

With water; acetic acid; triethylamine; sodium hydroxide; In ethanol; dimethyl sulfoxide; 1,2-dichloro-ethane;