Technology Process of Benzeneethanol, 4-broMo-beta-(cyclohexylMethylene)-, (betaE)-
There total 4 articles about Benzeneethanol, 4-broMo-beta-(cyclohexylMethylene)-, (betaE)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
toluene;
at -78 - 20 ℃;
for 18h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: NaOMe / methanol / 16 h / 50 °C
1.2: 75 percent / NaOH / methanol; H2O / 5 h / 50 °C
2.1: 86 percent / DIBAH / toluene / 16 h / -70 - 20 °C
With
sodium methylate; diisobutylaluminium hydride;
In
methanol; toluene;
DOI:10.1016/j.tetlet.2006.02.110
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 72 percent / AlCl3 / CH2Cl2 / 4 h / -10 - 20 °C
2.1: 80 percent / LiHMDS / tetrahydrofuran / 16 h / 0 - 20 °C
3.1: NaOMe / methanol / 16 h / 50 °C
3.2: 75 percent / NaOH / methanol; H2O / 5 h / 50 °C
4.1: 86 percent / DIBAH / toluene / 16 h / -70 - 20 °C
With
aluminium trichloride; sodium methylate; diisobutylaluminium hydride; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; dichloromethane; toluene;
1.1: Friedel-Crafts acylation / 2.1: Wittig reaction;
DOI:10.1016/j.tetlet.2006.02.110