(E)-2-(4-Bromophenyl)-3-cyclohexylacrylic acid

Base Information

• Chemical Name: (E)-2-(4-Bromophenyl)-3-cyclohexylacrylic acid
• CAS No.: 731018-46-5
• Molecular Formula: C15H17 Br O2
• Molecular Weight: 309.203
• DSSTox Substance ID: DTXSID80703608
• Wikidata: Q82635804
• Mol file: 731018-46-5.mol

Synonyms:731018-46-5;(E)-2-(4-Bromophenyl)-3-cyclohexylacrylic acid;(E)-2-(4-bromophenyl)-3-cyclohexylprop-2-enoic acid;(E)-2-(4-Bromophenyl)-3-cyclohexylacrylicacid;SCHEMBL1581911;DTXSID80703608;XRRNSLGIOAJLKB-GXDHUFHOSA-N;A837718;(E)-2-(4-Bromo-phenyl)-3-cyclohexyl-acrylic acid;(E)-2-(4-bromophenyl)-3-cyclohexyl-2-propenoic acid;(2E)-2-(4-Bromophenyl)-3-cyclohexylprop-2-enoic acid;(E)-2-(4-bromophenyl)-3-cyclohexyl-prop-2-enoic acid

Chemical Property of (E)-2-(4-Bromophenyl)-3-cyclohexylacrylic acid

Chemical Property:

• PSA: 37.30000
• LogP: 4.49740
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 308.04119
• Heavy Atom Count: 18
• Complexity: 311

Purity/Quality:

97% ^*data from raw suppliers

(E)-2-(4-Bromophenyl)-3-cyclohexylacrylicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)C=C(C2=CC=C(C=C2)Br)C(=O)O
• Isomeric SMILES: C1CCC(CC1)/C=C(\C2=CC=C(C=C2)Br)/C(=O)O

Technology Process of (E)-2-(4-Bromophenyl)-3-cyclohexylacrylic acid

There total 1 articles about (E)-2-(4-Bromophenyl)-3-cyclohexylacrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-bromo-phenyl)-3-cyclohexyl-acrylic acid ethyl ester (731018-45-4) → (E)-2-(4-bromo-phenyl)-3-cyclohexyl-acrylic acid (731018-46-5)

Guidance literature:

2-(4-bromo-phenyl)-3-cyclohexyl-acrylic acid ethyl ester; With sodium methylate; In methanol; at 50 ℃; for 72h;

With sodium hydroxide; water; In methanol; at 50 ℃; for 24 - 96h;

Reference yield:

(E)-2-(4-bromo-phenyl)-3-cyclohexyl-acrylic acid (731018-46-5) → (E)-2-(4-bromo-phenyl)-3-cyclohexyl-prop-2-en-1-ol (731018-47-6)

Guidance literature:

With diisobutylaluminium hydride; In toluene; at -78 - 20 ℃; for 18h;

upstream raw materials:

2-(4-bromo-phenyl)-3-cyclohexyl-acrylic acid ethyl ester

Downstream raw materials:

(E)-2-(4-bromo-phenyl)-3-cyclohexyl-prop-2-en-1-ol

Refernces