METHYL-3-ETHOXYISOTHIAZOLE-5-CARBOXYLATE

Base Information

Chemical Name:METHYL-3-ETHOXYISOTHIAZOLE-5-CARBOXYLATE
CAS No.:170953-74-9
Molecular Formula:C7H9NO3S
Molecular Weight:187.21626
Hs Code.:
Mol file:170953-74-9.mol

Synonyms:METHYL-3-ETHOXYISOTHIAZOLE-5-CARBOXYLATE;3-Ethoxy-5-isothiazolecarboxylic Acid Methyl Ester

Suppliers and Price of METHYL-3-ETHOXYISOTHIAZOLE-5-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl-3-ethoxyisothiazole-5-carboxylate
100mg
$ 220.00

Medical Isotopes, Inc.
Methyl-3-ethoxyisothiazole-5-carboxylate
0.5 g
$ 2000.00

American Custom Chemicals Corporation
METHYL-3-ETHOXYISOTHIAZOLE-5-CARBOXYLATE 95.00%
5MG
$ 498.50

Total 3 raw suppliers

Chemical Property of METHYL-3-ETHOXYISOTHIAZOLE-5-CARBOXYLATE

Chemical Property:

Melting Point:42-44°C
PSA：76.66000
LogP:1.32840
Storage Temp.:Refrigerator
Solubility.:Chloroform, Ether, Ethyl Acetate, Methanol

Purity/Quality:

97% ^*data from raw suppliers

Methyl-3-ethoxyisothiazole-5-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Synthesis and receptor binding of 5-(amino[3H]2methyl)-3-isothiazolol ([3H]thiomuscimol), a specific GABAA agonist photoaffinity label.

Technology Process of METHYL-3-ETHOXYISOTHIAZOLE-5-CARBOXYLATE

There total 1 articles about METHYL-3-ETHOXYISOTHIAZOLE-5-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 74-96-4
ethyl bromide

: 100241-89-2
methyl 3-hydroxyisothiazole-5-carboxylate

: 170953-74-9
methyl 3-ethoxyisothiazole-5-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 20h; Ambient temperature;
DOI:10.1002/jlcr.2580360909

Reference yield:

: 170953-74-9
methyl 3-ethoxyisothiazole-5-carboxylate

: 170953-78-3
3-ethoxy-5-chloromethylisothiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / NaBH₄ / methanol / 2.5 h / 25 °C

2: 80 percent / SOCl₂ / 1 h / Heating

With sodium tetrahydroborate; thionyl chloride; In methanol;
DOI:10.1002/jlcr.2580360909