3,6-Di-O-benzoyl-D-galactal

Base Information

• Chemical Name: 3,6-Di-O-benzoyl-D-galactal
• CAS No.: 130323-36-3
• Molecular Formula: C20H18O6
• Molecular Weight: 354.35
• DSSTox Substance ID: DTXSID30463184
• Nikkaji Number: J1.516.327E
• Mol file: 130323-36-3.mol

Synonyms:3,6-Di-O-benzoyl-D-galactal;130323-36-3;[(2R,3R,4R)-4-benzoyloxy-3-hydroxy-3,4-dihydro-2H-pyran-2-yl]methyl benzoate;3 6-DI-O-BENZOYL-D-GALACTAL 97;((2R,3R,4R)-4-(Benzoyloxy)-3-hydroxy-3,4-dihydro-2H-pyran-2-yl)methylbenzoate;DTXSID30463184;((2R,3R,4R)-4-(Benzoyloxy)-3-hydroxy-3,4-dihydro-2H-pyran-2-yl)methyl benzoate

Chemical Property of 3,6-Di-O-benzoyl-D-galactal

Chemical Property:

• Vapor Pressure: 1.04E-11mmHg at 25°C
• Melting Point: 122-124 °C(lit.)
• Boiling Point: 521.6°C at 760 mmHg
• Flash Point: 185.4°C
• PSA: 82.06000
• Density: 1.32g/cm³
• LogP: 2.34240
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 354.11033829
• Heavy Atom Count: 26
• Complexity: 504

Purity/Quality:

95% ^*data from raw suppliers

3,6-Di-O-benzoyl-D-galactal Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)OCC2C(C(C=CO2)OC(=O)C3=CC=CC=C3)O
• Isomeric SMILES: C1=CC=C(C=C1)C(=O)OC[C@@H]2[C@@H]([C@@H](C=CO2)OC(=O)C3=CC=CC=C3)O

Technology Process of 3,6-Di-O-benzoyl-D-galactal

There total 4 articles about 3,6-Di-O-benzoyl-D-galactal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C29H38O6Si (356060-86-1) → 3,6-di-O-benzoyl-D-galactal (130323-36-3)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/S0040-4039(01)00611-6

Reference yield: 76.0%

benzoyl chloride (98-88-4) + D-galactal (21193-75-9) → 3,6-di-O-benzoyl-D-galactal (130323-36-3)

Guidance literature:

With pyridine; methanol; In 1,2-dichloro-ethane; 1) 45 min, 0 deg C, 2) 30 min, room temperature;

DOI:10.1016/0008-6215(90)84259-W

Reference yield:

triacetyl-D-galactal (4098-06-0) → 3,6-di-O-benzoyl-D-galactal (130323-36-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / sodium, methanol

2: 76 percent / 1) pyridine, 2) methanol / 1,2-dichloro-ethane / 1) 45 min, 0 deg C, 2) 30 min, room temperature

With pyridine; methanol; sodium; In 1,2-dichloro-ethane;

DOI:10.1016/0008-6215(90)84259-W

upstream raw materials:

benzoyl chloride

D-galactal

C₂₉H₃₈O₆Si

triacetyl-D-galactal

Downstream raw materials:

C₂₁H₂₀O₈S