Nα,Nα,Nε,Nε-Tetramethyl-L-lysine ethyl ester

Base Information

• Chemical Name: Nα,Nα,Nε,Nε-Tetramethyl-L-lysine ethyl ester
• CAS No.: 55836-53-8
• Molecular Formula: C₁₂H₂₆N₂O₂
• Molecular Weight: 230.351
• Mol file: 55836-53-8.mol

Synonyms:N2,N2,N6,N6-Tetramethyl-L-lysine ethyl ester;Nα,Nα,Nε,Nε-Tetramethyl-L-lysine ethyl ester

Chemical Property of Nα,Nα,Nε,Nε-Tetramethyl-L-lysine ethyl ester

Chemical Property:

• Boiling Point: 285.9±35.0 °C(Predicted)
• PKA: 9.70±0.28(Predicted)
• PSA: 0.00000
• Density: 0.940±0.06 g/cm3(Predicted)
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Nα,Nα,Nε,Nε-Tetramethyl-L-lysine ethyl ester

There total 2 articles about Nα,Nα,Nε,Nε-Tetramethyl-L-lysine ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nα,Nα,Nε,Nε-tetramethyllysine (92175-43-4) + ethanol (64-17-5) → (S)-(-)-Ethyl-N(α),N(α),N(ε),N(ε)-Tetramethyl-lysinat (55836-53-8)

Guidance literature:

N_α,N_α,N_ε,N_ε-tetramethyllysine; ethanol; With sodium hydroxide; In water; for 0.0166667h; pH=> 9;

With pyridine; chloroformic acid ethyl ester; In water;

DOI:10.1002/jms.3788

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethanol (64-17-5) + L-Lysine hydrochloride (657-27-2,10098-89-2,26124-78-7) → (S)-(-)-Ethyl-N(α),N(α),N(ε),N(ε)-Tetramethyl-lysinat (55836-53-8)

Guidance literature:

Multistep reaction; (i) Pd-C, H₂, H₂O, (ii) /BRN= 1718733/, HCl;

DOI:10.1248/cpb.25.1273

upstream raw materials:

formaldehyd

ethanol

L-Lysine hydrochloride

N_α,N_α,N_ε,N_ε-tetramethyllysine

Refernces

• 1、 Kitamoto,Kameo,Terashima,Yamada. "Stereochemical studies. XLVII. Asymmetric reduction of 2-alkyl-1,3,4-cyclopentanetriones with lithium aluminum hydride decomposed by optically active β-aminoalcohols. Syntheses of optically active allethrolone and prostaglandin E1". . p. 1273 - 1284. Retrieved 2007/10/05.