Methyl 2-Acetoxy-4-broMobutanoate

Base Information

• Chemical Name: Methyl 2-Acetoxy-4-broMobutanoate
• CAS No.: 76799-57-0
• Molecular Formula: C7H11BrO4
• Molecular Weight: 239.06384
• Mol file: 76799-57-0.mol

Synonyms:Methyl 2-Acetoxy-4-broMobutanoate

Chemical Property of Methyl 2-Acetoxy-4-broMobutanoate

Chemical Property:

• PSA: 52.60000
• LogP: 0.87610

Purity/Quality:

97% ^*data from raw suppliers

METHYL2-ACETOXY-4-BROMOBUTANOATE 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 2-Acetoxy-4-broMobutanoate

There total 1 articles about Methyl 2-Acetoxy-4-broMobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

methyl 2,4-dibromobutanoate (29547-04-4,70288-65-2) + sodium acetate (127-09-3) → methyl 2-acetoxy-4-bromobutyrate (76799-57-0)

Guidance literature:

In N,N-dimethyl-formamide; 1.) RT, 18 h, 2.) 50 deg C, 1 h;

DOI:10.1021/jm00136a011

Reference yield: 78.0%

methyl 2-acetoxy-4-bromobutyrate (76799-57-0) + 4-Hydroxyacetophenone (99-93-4) → 4-<3-(carbomethoxy)-3-acetoxypropoxy>acetophenone (80502-27-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; 1.) room temp., 16 h, 2.) 50 deg C, 3 h, 3.) 70 deg C, 2 h;

DOI:10.1021/jo00346a030

Reference yield: 76.0%

(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone (520-33-2,41001-90-5,69097-99-0) + methyl 2-acetoxy-4-bromobutyrate (76799-57-0) → 3',5-dihydroxy-4'-methoxy-7-(3-acetoxy-3-carbomethoxypropoxy)flavanone (76799-58-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 72h; Ambient temperature;

DOI:10.1021/jm00136a011

upstream raw materials:

methyl 2,4-dibromobutanoate

sodium acetate

Downstream raw materials:

3',5-dihydroxy-4'-methoxy-7-(3-acetoxy-3-carbomethoxypropoxy)flavanone

4-<3-(carbomethoxy)-3-acetoxypropoxy>acetophenone