(3aR,3aα,7aα)-Octahydro-2-(2-O,3-O-isopropylidene-β-D-ribofuranosyl)-1,2-benzisoxazole

Base Information

• Chemical Name: (3aR,3aα,7aα)-Octahydro-2-(2-O,3-O-isopropylidene-β-D-ribofuranosyl)-1,2-benzisoxazole
• CAS No.: 64018-62-8
• Molecular Weight: 299.36
• Mol file: 64018-62-8.mol

Synonyms:(3aR,3aα,7aα)-Octahydro-2-(2-O,3-O-isopropylidene-β-D-ribofuranosyl)-1,2-benzisoxazole

Chemical Property of (3aR,3aα,7aα)-Octahydro-2-(2-O,3-O-isopropylidene-β-D-ribofuranosyl)-1,2-benzisoxazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3aR,3aα,7aα)-Octahydro-2-(2-O,3-O-isopropylidene-β-D-ribofuranosyl)-1,2-benzisoxazole

There total 2 articles about (3aR,3aα,7aα)-Octahydro-2-(2-O,3-O-isopropylidene-β-D-ribofuranosyl)-1,2-benzisoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + O2,O3-isopropylidene-O5-trityl-D-ribose oxime (63535-44-4,63535-45-5,64044-16-2) + cyclohexene (110-83-8) → 1-(hexahydro-benzo[d]isoxazol-2-yl)-O2,O3-isopropylidene-β-D-1-deoxy-ribofuranose (64018-62-8,64044-17-3,145632-12-8) + 1-(hexahydro-benzo[d]isoxazol-2-yl)-O2,O3-isopropylidene-β-D-1-deoxy-ribofuranose (64018-62-8,64044-17-3,145632-12-8)

Guidance literature:

Multistep reaction; (i) molecular sieves, (ii) FeCl₃, CH₂Cl₂;

DOI:10.1002/hlca.19770600417

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + O2,O3-isopropylidene-O5-trityl-D-ribose oxime (63535-44-4,63535-45-5,64044-16-2) + cyclohexene (110-83-8) → 1-(hexahydro-benzo[d]isoxazol-2-yl)-O2,O3-isopropylidene-β-D-1-deoxy-ribofuranose (64018-62-8,64044-17-3,145632-12-8) + 1-(hexahydro-benzo[d]isoxazol-2-yl)-O2,O3-isopropylidene-β-D-1-deoxy-ribofuranose (64018-62-8,64044-17-3,145632-12-8)

Guidance literature:

Multistep reaction; (i) molecular sieves, (ii) FeCl₃, CH₂Cl₂;

DOI:10.1002/hlca.19770600417

Reference yield:

1-(hexahydro-benzo[d]isoxazol-2-yl)-O2,O3-isopropylidene-β-D-1-deoxy-ribofuranose (64018-62-8,64044-17-3,145632-12-8) → octahydro-benzo[d]isoxazole (64018-30-0,64044-13-9,92843-50-0)

Guidance literature:

With perchloric acid;

DOI:10.1002/hlca.19770600417

upstream raw materials:

formaldehyd

O²,O³-isopropylidene-O⁵-trityl-D-ribose oxime

cyclohexene

Downstream raw materials:

octahydro-benzo[d]isoxazole

(3aR*,7aR*)-1,2-benzisoxazol