(S)-CARNITINE MESYLATE, MESLATE SALT

Base Information

• Chemical Name: (S)-CARNITINE MESYLATE, MESLATE SALT
• CAS No.: 161886-60-8
• Molecular Formula: CH₃O₃S*C₈H₁₈NO₅S
• Molecular Weight: 335.4
• Mol file: 161886-60-8.mol

Synonyms:(S)-CARNITINE MESYLATE, MESLATE SALT;(S)-3-Carboxy-N,N,N-triMethyl-2-[(Methylsulfonyl)oxy]-1-propanaMiniuM Methanesulfonate

Chemical Property of (S)-CARNITINE MESYLATE, MESLATE SALT

Chemical Property:

• Melting Point: 148-150°C dec.
• Storage Temp.: Refrigerator, Under Inert Atmosphere

Purity/Quality:

97% ^*data from raw suppliers

(S)-CarnitineMesylate,MesylateSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (S)-Carnitine Mesylate, Mesylate Salt (cas# 161886-60-8) is a compound useful in organic synthesis.

Technology Process of (S)-CARNITINE MESYLATE, MESLATE SALT

There total 7 articles about (S)-CARNITINE MESYLATE, MESLATE SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

((R)-3-Benzyloxycarbonyl-2-methanesulfonyloxy-propyl)-trimethyl-ammonium; perchlorate → (R)-carnitine mesylate mesylate (161886-60-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; for 4h; under 2327.2 Torr;

Reference yield: 90.0%

(S)-carnitine mesylate isobutyl ester mesylate (161886-59-5) → (S)-carnitine mesylate mesylate (161886-60-8)

Guidance literature:

With hydrogenchloride; at 50 ℃; for 20h;

Reference yield:

L-carnitine chloride (6645-46-1) → (R)-carnitine mesylate mesylate (161886-60-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) HCl, 2.) Amberlite IRA-402 (ClO₄^- form)

2: pyridine / 1.75 h

3: 99 percent / H₂ / 10percent Pd/C / 4 h / 2327.2 Torr

With pyridine; hydrogenchloride; Amberlite IRA-402 (ClO₄^- form); hydrogen; palladium on activated charcoal;

upstream raw materials:

(S)-carnitine mesylate isobutyl ester mesylate

(S)-(+)-3-hydroxy-4-(trimethylammonio)-butanoic acid chloride

(S)-(+)-Carnitinamid-Hydrochlorid

L-carnitine chloride

Refernces

• 1、 Bernabei, Ida,Castagnani, Roberto,Angelis, Francesco De,Witt Scalfaro, Paolo De,Giannessi, Fabio,et al.. "Vollstaendig enantioselektive Inversion der Konfiguration von (S)-(+)-Carnitinen". . p. 2202 - 2203. Retrieved 2007/10/02.