6645-46-1 Usage
Description
L(-)-Carnitine hydrochloride, also known as Levocarnitine hydrochloride, is a naturally occurring compound derived from the amino acids lysine and methionine. It is a white to slightly beige crystalline powder that plays a crucial role in the metabolism of fatty acids. L(-)-Carnitine hydrochloride is essential for the transport of long-chain fatty acids into the mitochondria for energy production.
Uses
Used in Pharmaceutical Industry:
L(-)-Carnitine hydrochloride is used as a pharmaceutical agent for the treatment of various conditions related to fatty acid metabolism, including primary and secondary carnitine deficiency, certain inborn errors of metabolism, and to support cardiovascular health.
Used in Research Applications:
L(-)-Carnitine hydrochloride is used as a research tool to study the function and regulation of ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5, which are involved in the transport of carnitine and other compounds across cell membranes.
Used in Mitochondrial Function Studies:
L(-)-Carnitine hydrochloride is used in research to allow the entry of palmitic acid into the mitochondria, which is essential for the oxidation of fatty acids and energy production in cells.
Used in Sports Nutrition:
L(-)-Carnitine hydrochloride is used as a dietary supplement in the sports nutrition industry to enhance endurance, improve muscle function, and support overall athletic performance.
Used in Animal Nutrition:
L(-)-Carnitine hydrochloride is used as a feed additive in the animal nutrition industry to improve the health and growth of livestock, particularly in poultry and swine, by enhancing fatty acid metabolism and energy utilization.
Used in Cosmetics Industry:
L(-)-Carnitine hydrochloride is used in the cosmetics industry for its potential skin health benefits, including the promotion of skin firmness and elasticity, as well as its antioxidant properties.
Check Digit Verification of cas no
The CAS Registry Mumber 6645-46-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,4 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6645-46:
(6*6)+(5*6)+(4*4)+(3*5)+(2*4)+(1*6)=111
111 % 10 = 1
So 6645-46-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H/t6-;/m1./s1
6645-46-1Relevant articles and documents
NOVEL CRYSTALLINE FORMS
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Page/Page column 12; 13, (2017/12/01)
Preparation and characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl) phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
Asymmetric synthesis of l-carnitine from (R)-3-chloro-1,2-propanediol
Li, Xu Qin,Yang, Yun Xu,Wang, Wei Li,Hu, Bin,Xue, Hui Min,Zhang, Tian Yi,Zhang, Xue Tao
body text, p. 765 - 767 (2012/01/03)
A practical chemical synthesis of l-carnitine (1) has been accomplished from (R)-3-chloro-1,2-propanediol ((R)-4), which is a main by-product originated from (R,R)-Salen Co(III) catalyzed hydrolytic kinetic resolution (HKR) of (±)-epichlorohydrin. (R)-4 was utilized as a chiral starting material to prepare the key intermediate cyclic sulfite ((R)-5). The new synthetic approach demonstrated an efficient utilization of organic by-product for the asymmetric synthesis of bioactive compounds.
PROCESS FOR L-CARNITINE AND ACETYL L-CARNITINE HYDROCHLORIDE
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Page/Page column 9-10, (2010/11/29)
Provided is a process for preparing L-carnitine or acetyl L-carnitine hydrochloride. Specifically, the process comprises sequentially synthesizing racemic 4-chloro-3-hydroxybutyronitrile and racemic 4-chloro-3-hydroxy butyric acid alkyl ester under specific reaction conditions, using racemic epichlorohydrin as a starting material, preparing (R)-4-chloro-3-hydroxy butyric acid alkyl ester from stereoselective hydrolysis of the racemic 4-chloro-3-hydroxy butyric acid alkyl ester using an enzyme, and preparing L-carnitine or acetyl L-carnitine hydrochloride from the (R)-4-chloro-3-hydroxy butyric acid alkyl ester, according to the known method.