4-Deoxy-D-Glucose

Base Information

• Chemical Name: 4-Deoxy-D-Glucose
• CAS No.: 23397-23-1
• Molecular Formula: C₆H₁₂O₅
• Molecular Weight: 164.158
• Mol file: 23397-23-1.mol

Synonyms:4-DEOXY-D-GLUCOSE;D-XYLO-HEXOPYRANOSE, 4-DEOXY-;(3R,4S,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4-triol;REF DUPL: 4-Deoxy-D-Glucose

Chemical Property of 4-Deoxy-D-Glucose

Chemical Property:

• PSA: 97.99000
• LogP: -2.34960
• Storage Temp.: -20°C Freezer
• Solubility.: Water

Purity/Quality:

98%Min ^*data from raw suppliers

4-Deoxy-D-glucose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A potential inhibitor for lactose synthase.

Technology Process of 4-Deoxy-D-Glucose

There total 55 articles about 4-Deoxy-D-Glucose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl 2,3,6-tri-O-benzyl-4-deoxy-D-xylo-hexopyranoside (784179-22-2) → 4-deoxy-D-galactose (24707-41-3,24707-42-4,28434-38-0,34339-27-0,34339-29-2,69088-89-7,70004-74-9,101470-45-5,141611-79-2,23397-23-1)

Guidance literature:

With hydrogen; palladium dihydroxide; In methanol; at 20 ℃;

DOI:10.1021/ja048054m

Reference yield: 100.0%

methyl 4-deoxy-β-D-xylo-hexopyranoside (51385-57-0) → 4-deoxy-β-D-xylo-hexopyranose (23397-23-1)

Guidance literature:

With hydrogenchloride; In water; at 70 ℃; for 24h; pH=1.5;

DOI:10.1021/acscatal.1c04679

Reference yield: 96.0%

(-)-5-O-benzyl-6-O-(t-butyl)dimethylsilyl-4-deoxy-2,3-O-isopropylidene-D-lyxo-hexose (128503-24-2) → 4-deoxy-D-mannopyranoside (24707-42-4,23397-23-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 25 ℃; for 48h;

DOI:10.1016/S0040-4039(00)70712-X

upstream raw materials:

methyl 4-deoxy-β-D-xylo-hexopyranoside

methyl 4-deoxy-α-D-xylo-hexopyranoside

1,2,3,6-tetra-O-benzoyl-4-deoxy-α-D-xylo-hexopyranose

methyl 4-deoxy-α-D-xylo-hexopyranosyl-(1<*>6)-α-D-glucopyranoside

Downstream raw materials:

1,2,4-tri-O-acetyl-3-deoxy-6-O-triphenylmethyl-D-glucopyranose