N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide

Base Information

Chemical Name:N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide
CAS No.:1256360-27-6
Molecular Formula:C14H22BNO5S
Molecular Weight:327.209
Hs Code.:2935009090
DSSTox Substance ID:DTXSID00682345
Wikidata:Q82606679
Mol file:1256360-27-6.mol

Synonyms:1256360-27-6;N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide;4-methoxy-3-(methylsulfonylamino)phenylboronic acid, pinacol ester;N-[2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanesulfonamide;4-Methoxy-3-(methylsulfonylamino)phenylboronic acid pinacol ester;SCHEMBL15308560;DTXSID00682345;MFCD16660308;AKOS022184166;BS-26516;CS-0176623;4-Methoxy-3-(methylsulfonylamino)phenylboronic acid, pinacol ester, AldrichCPR;N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methane sulfonamide

Suppliers and Price of N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methoxy-3-(methylsulfonylamino)phenylboronicacid,pinacolester
100mg
$ 200.00

TRC
4-Methoxy-3-(methylsulfonylamino)phenylboronicacid,pinacolester
10mg
$ 45.00

Crysdot
N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide 95+%
250mg
$ 327.00

Crysdot
N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide 95+%
1g
$ 683.00

AK Scientific
4-Methoxy-3-(methylsulfonylamino)phenylboronicacidpinacolester
250mg
$ 344.00

Total 8 raw suppliers

Chemical Property of N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide

Chemical Property:

PSA：82.24000
LogP:2.51970
Storage Temp.:Room temperature.
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:327.1311741
Heavy Atom Count:22
Complexity:486

Purity/Quality:

95% ^*data from raw suppliers

4-Methoxy-3-(methylsulfonylamino)phenylboronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(C=C2)OC)NS(=O)(=O)C

Technology Process of N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide

There total 3 articles about N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: N-(5-bromo-2-methoxyphenyl)methanesulfonamide

: 73183-34-3
bis(pinacol)diborane

: 1256360-27-6
N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; at 80 ℃; for 2h; Inert atmosphere;

Reference yield:

: 6358-77-6
5-bromo-2-methoxyaniline

: 1256360-27-6
N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 0.5 h / 0 °C

2: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 2 h / 80 °C / Inert atmosphere

With pyridine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; dichloromethane;

Reference yield:

: 1256360-27-6
N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide

Guidance literature:: In 1,2-dimethoxyethane; for 0.166667h; Inert atmosphere;

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,2-dimethoxyethane; at 80 ℃; Inert atmosphere;