ethyl N-benzamidocarbamate

Base Information

• Chemical Name: ethyl N-benzamidocarbamate
• CAS No.: 10465-97-1
• Molecular Formula: C10H12 N2 O3
• Molecular Weight: 208.217
• NSC Number: 140714
• DSSTox Substance ID: DTXSID00301044
• Nikkaji Number: J2.699.324E
• Wikidata: Q82044576
• Mol file: 10465-97-1.mol

Synonyms:ethyl N-benzamidocarbamate;10465-97-1;1PhCO 2EtOCO hy;1-Benzoyl-2-carboethoxyhydrazine;DTXSID00301044;RDGMCHMEQAKGEG-UHFFFAOYSA-N;N-benzamidocarbamic acid ethyl ester;NSC140714;STK422190;Ethyl 2-benzoylhydrazinecarboxylate #;AKOS003238170;NSC-140714;ethyl 2-(phenylcarbonyl)hydrazinecarboxylate;A801049;Hydrazinecarboxylic acid, 2-benzoyl-, ethyl ester

Chemical Property of ethyl N-benzamidocarbamate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.189g/cm³
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 208.08479225
• Heavy Atom Count: 15
• Complexity: 225

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)NNC(=O)C1=CC=CC=C1

Technology Process of ethyl N-benzamidocarbamate

There total 9 articles about ethyl N-benzamidocarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

chloroformic acid ethyl ester (541-41-3) + benzoic acid hydrazide (613-94-5) → N-benzoyl-N'-ethoxycarbonyl hydrazine (10465-97-1)

Guidance literature:

With sodium carbonate; In tetrahydrofuran; water; at 0 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1002/ejoc.200900013

Reference yield:

1-benzoyl-1H-benzotriazole (4231-62-3) + ethylhydrazine carboxylate (4114-31-2) → N-benzoyl-N'-ethoxycarbonyl hydrazine (10465-97-1)

Guidance literature:

With dmap; potassium carbonate; In dichloromethane; at 25 ℃; for 0.166667h; Reagent/catalyst; Sonication;

DOI:10.1021/acs.joc.7b01863

Reference yield:

benzoic acid (65-85-0,8013-63-6) → N-benzoyl-N'-ethoxycarbonyl hydrazine (10465-97-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid / Reflux

2: hydrazine hydrate / Reflux

3: potassium carbonate / toluene / 5 h / Reflux

With sulfuric acid; potassium carbonate; hydrazine hydrate; In toluene;

DOI:10.1002/jhet.3110

upstream raw materials:

chloroformic acid ethyl ester

benzoic acid hydrazide

benzoyl-diazenecarboxylic acid ethyl ester

2-phenyl-4-ethoxycarbonyl-1,3,4-oxadiazol-5(4H)-one

Downstream raw materials:

5-phenyl-1,3,4-thiadiazolin-2-one

2-phenyl-1,3,4-thiadiazole-5(4H)-thione

5-phenyl-1,3,4-thiadiazole-2(3H)-thione

2-ethoxy-5-phenyl-1,3,4-selenadiazole