Ethyl 2-(piperidin-4-ylidene)acetate

Base Information

Chemical Name:Ethyl 2-(piperidin-4-ylidene)acetate
CAS No.:315203-51-1
Molecular Formula:C9H15NO2
Molecular Weight:169.224
Hs Code.:2933399090
DSSTox Substance ID:DTXSID30595656
Nikkaji Number:J1.405.005A
Mol file:315203-51-1.mol

Synonyms:Ethyl 2-(piperidin-4-ylidene)acetate;315203-51-1;ethyl 2-piperidin-4-ylideneacetate;Piperidin-4-ylidene-acetic acid ethyl ester;ethyl 4-piperidinylideneacetate;SCHEMBL5154874;DTXSID30595656;VAYPMPDBKBYGSQ-UHFFFAOYSA-N;Ethyl (piperidin-4-ylidene)acetate;AMY42338;Ethyl2-(piperidin-4-ylidene)acetate;MFCD11007803;4-(ethoxycarbonylmethylidene)piperidine;AKOS006304889;SB22808;AS-65922;SY253736;DB-068470;CS-0060755;2-(4-piperidinylidene)-Acetic acid ethyl ester;W18114;EN300-1455301

Suppliers and Price of Ethyl 2-(piperidin-4-ylidene)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Piperidin-4-ylidene-aceticacidethylester
10mg
$ 90.00

TRC
Piperidin-4-ylidene-aceticacidethylester
2mg
$ 60.00

American Custom Chemicals Corporation
PIPERIDIN-4-YLIDENE-ACETIC ACID ETHYL ESTER 95.00%
5MG
$ 501.71

AK Scientific
ethyl2-piperidin-4-ylideneacetate
250mg
$ 285.20

AccelPharmtech
2-(4-piperidinylidene)-Aceticacidethylester 97.00%
5G
$ 4530.00

AccelPharmtech
2-(4-piperidinylidene)-Aceticacidethylester 97.00%
1G
$ 2640.00

Total 3 raw suppliers

Chemical Property of Ethyl 2-(piperidin-4-ylidene)acetate

Chemical Property:

PSA：38.33000
LogP:1.18810
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:169.110278721
Heavy Atom Count:12
Complexity:179

Purity/Quality:

97% ^*data from raw suppliers

Piperidin-4-ylidene-aceticacidethylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=C1CCNCC1

Technology Process of Ethyl 2-(piperidin-4-ylidene)acetate

There total 3 articles about Ethyl 2-(piperidin-4-ylidene)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 82244-11-9
ethyl-1-carbobenzoxy-Δ^4,α-piperidine-4-acetate

: 59184-90-6
ethyl (piperidin-4-yl)acetate

: 315203-51-1
ethyl 2-(piperidin-4-ylidene)acetate

Guidance literature:: With hydrogen; palladium on activated charcoal; ethylenediamine; In methanol; at 20 ℃; for 0.75h; under 760 Torr;
DOI:10.1016/S0040-4020(00)00771-7

Reference yield:

: 82244-11-9
ethyl-1-carbobenzoxy-Δ^4,α-piperidine-4-acetate

: 59184-90-6
ethyl (piperidin-4-yl)acetate

: 315203-51-1
ethyl 2-(piperidin-4-ylidene)acetate

: N-benzyloxycarbonyl-4-(ethoxycarbonylmethyl)piperidine

Guidance literature:: With hydrogen; palladium on activated charcoal; ethylenediamine; In 1,4-dioxane; at 20 ℃; under 760 - 3800 Torr; Further Variations:; Solvents; Pressures; Product distribution; Kinetics;
DOI:10.1016/S0040-4020(00)00771-7

Reference yield:

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 315203-51-1
ethyl 2-(piperidin-4-ylidene)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / tetrahydrofuran / 43 h / Heating

2: 64 percent Spectr_. / H₂ / Pd/C-ethylenediamine / methanol / 0.75 h / 20 °C / 760 Torr

With hydrogen; palladium on activated charcoal; ethylenediamine; In tetrahydrofuran; methanol; 1: Condensation / 2: Hydrogenolysis;
DOI:10.1016/S0040-4020(00)00771-7