82244-11-9

Basic information

• Product Name: Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate
• Synonyms: Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate
• CAS NO: 82244-11-9
• Molecular Weight: 303.358
• Mol File: 82244-11-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate(82244-11-9)
• EPA Substance Registry System: Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate(82244-11-9)

Safety Data

• Hazardous Substances Data: 82244-11-9(Hazardous Substances Data)

Usage

General Description

Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate is a chemical compound with the molecular formula C22H25NO4. It is a piperidine derivative containing a benzyl group and an ethoxy-oxoethylidene group. Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate is commonly used as an intermediate in the synthesis of pharmaceuticals, particularly in the production of drugs that target the central nervous system. It has also been studied for its potential neurological effects and its activity as a GABA receptor antagonist. Additionally, it has been used in research and development of new pharmaceutical compounds.

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 501-53-1 benzyl chloroformate 
• 311-46-6 ethyl 2-(dimethoxyphosphoryl)acetate 
• 5927-18-4 trimethyl phosphonoacetate 
• 41979-39-9 4-piperidone hydrochloride 
• 95798-23-5 1-(benzyloxycarbonyl)-4-hydroxypiperidine 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 147610-84-2 6-benzyl 1-ethyl 6-azaspiro[2.5]octane-1,6-dicarboxylate 
• 130312-10-6 benzyl 4-(2-oxoethyl)piperidine-1-carboxylate 
• 115909-91-6 1-(Benzyloxycarbonyl)-4-(2-hydroxyethyl)piperidine 
• 82244-13-1 ethyl 1-carbobenzoxy-3,4-epoxypiperidine-4-acetate 
• 82244-14-2 1-carbobenzoxy-3,4-dihydroxypiperidine-4-acetic acid lactone 
• 82244-15-3 1-carbobenzoxy-Δ^4,α-piperidine-4,3-acetolactone 
• 82244-16-4 cis-1-carbobenzoxypiperidine-4,3-acetolactone 
• 59184-90-6 ethyl (piperidin-4-yl)acetate 
• 315203-51-1 ethyl 2-(piperidin-4-ylidene)acetate 
• 82244-12-0 ethyl 1-carbobenzoxy-1,2,5,6-tetrahydropyridine-4-acetate 

Relevant articles and documents

PIPERIDINE DERIVATIVES AS LIVER X RECEPTOR β AGONISTS, COMPOSITIONS, AND THEIR USE

Piperidine compounds of the Formular: (I) and pharmaceutically acceptable salts thereof, wherein X, Y, R 1, R 2, R 3, L, R 4, L 1, Q and R 5 are as defined herein. The compounds and pharmaceutically acceptable compositions comprising a compound thereof, are useful as Liver X-β receptor (LXRβ) agonists, and may be useful for treating or preventing pathologies related thereto. Such pathologies include, but are not limited to, inflammatory diseases and diseases characterized by defects in cholesterol and lipid metabolism, such as Alzheimer's disease.

ARYL AND HETEROARYL ETHER DERIVATIVES AS LIVER X RECEPTOR β AGONISTS, COMPOSITIONS, AND THEIR USE

Substituted aryl and heteroaryl ether compounds of the Formula (I) and pharmaceutically acceptable salts thereof, wherein X, R 1, R 2, R 3, L, R 4, L 1, Q, and R 5 are as defined herein. These compounds and pharmaceutically acceptable compositions comprising a compound thereof, are useful as Liver X-β receptor (LXRβ) agonists, and may be useful for treating or preventing pathologies related thereto. Such pathologies include, but are not limited to, inflammatory diseases and diseases characterized by defects in cholesterol and lipid metabolism, such as Alzheimer's disease.

SPIROCYCLOPROPYL PIPERIDINE DERIVATIVES

Disclosed herein is at least one piperidine derivative, at least one pharmaceutical composition comprising at least one piperidine derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith