Benzyl N-Acetyl-4,6-O-benzylidene-α-isoMuraMic Acid Methyl Ester

Base Information

• Chemical Name: Benzyl N-Acetyl-4,6-O-benzylidene-α-isoMuraMic Acid Methyl Ester
• CAS No.: 104371-52-0
• Molecular Formula: C₂₆H₃₁NO₈
• Molecular Weight: 485.534
• Mol file: 104371-52-0.mol

Synonyms:Benzyl N-Acetyl-4,6-O-benzylidene-α-isoMuraMic Acid Methyl Ester;2-AcetaMido-4,6-O-benzylidene-3-O-(L-1-carboxyethyl)-2-deoxy-α-D-glucopyranoside Benzyl Methyl Ester;N-Acetyl-1-O-(phenylMethyl)-4,6-O-(phenylMethylene)-α-isoMuraMic Acid Methyl Ester;N-Acetyl-1-O-(phenylmethyl)-4,6-O-(phenylmethylene)-alpha-isomuramic acid methyl ester

Chemical Property of Benzyl N-Acetyl-4,6-O-benzylidene-α-isoMuraMic Acid Methyl Ester

Chemical Property:

• Solubility.: Dichloromethane, Methanol

Purity/Quality:

97% ^*data from raw suppliers

Benzyl N-acetyl-4,6-O-benzylidene-a-isomuramic acid methyl ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A derivative of isomuramic acid.

Technology Process of Benzyl N-Acetyl-4,6-O-benzylidene-α-isoMuraMic Acid Methyl Ester

There total 5 articles about Benzyl N-Acetyl-4,6-O-benzylidene-α-isoMuraMic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl 4,6-O-benzylidene-2-acetylamino-2-deoxy-α-D-glucopyranoside (13343-63-0) + (R,S)-2-chloropropionic acid (598-78-7) + methyl iodide (74-88-4) → Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-(methoxycarbonyl)ethyl>-α-D-glucopyranoside (104371-51-9) + Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(S)-1-(methoxycarbonyl)ethyl>-α-D-glucopyranoside (104371-52-0)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1002/jlac.198619860104

Reference yield:

→ 2-((4aR,6R,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionic acid methyl ester (19229-58-4,24909-41-9,66141-63-7,85027-00-5,104371-51-9,104371-52-0)

Guidance literature:

2, Diazomethan;

DOI:10.1016/S0008-6215(00)85075-2

Reference yield:

→ (R)-2-((4aR,6S,7R,8R,8aR)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionic acid methyl ester (19229-58-4,24909-41-9,66141-63-7,85027-00-5,104371-51-9,104371-52-0)

Guidance literature:

Saeure 2, CH2N2;

DOI:10.1016/S0008-6215(00)80461-9

upstream raw materials:

benzyl 4,6-O-benzylidene-2-acetylamino-2-deoxy-α-D-glucopyranoside

(R,S)-2-chloropropionic acid

methyl iodide

Downstream raw materials:

benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(D-1-carboxyethyl)-α-D-glucopyranoside

Refernces