N5-[(2,4-Dimethoxyphenyl)methyl]-N2-[(benzyloxy)carbonyl]-L-glutamine 4-nitrophenyl ester

Base Information

Chemical Name:N5-[(2,4-Dimethoxyphenyl)methyl]-N2-[(benzyloxy)carbonyl]-L-glutamine 4-nitrophenyl ester
CAS No.:31874-53-0
Molecular Formula:C₂₈H₂₉N₃O₉
Molecular Weight:551.553
Hs Code.:
Mol file:31874-53-0.mol

Synonyms:N5-[(2,4-Dimethoxyphenyl)methyl]-N2-[(benzyloxy)carbonyl]-L-glutamine 4-nitrophenyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N5-[(2,4-Dimethoxyphenyl)methyl]-N2-[(benzyloxy)carbonyl]-L-glutamine 4-nitrophenyl ester

Chemical Property:

Melting Point:149 - 150 °C (ethanol)
Boiling Point:795.4±60.0 °C(Predicted)
PKA:10.44±0.46(Predicted)
PSA：158.01000
Density:1.294±0.06 g/cm3(Predicted)
LogP:5.21400

Purity/Quality:

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Technology Process of N5-[(2,4-Dimethoxyphenyl)methyl]-N2-[(benzyloxy)carbonyl]-L-glutamine 4-nitrophenyl ester

There total 4 articles about N5-[(2,4-Dimethoxyphenyl)methyl]-N2-[(benzyloxy)carbonyl]-L-glutamine 4-nitrophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 31874-34-7
2,4-dimethoxybenzaldoxime

: 31874-53-0
Z-Gln(Dmb)-ONp

Guidance literature:: Multi-step reaction with 3 steps

1: (i) Na2(OCH₂CH₂OCH₃)2>, (ii) /BRN= 2567599/

2: aq. NaOH

3: DCC

With sodium hydroxide; dicyclohexyl-carbodiimide;
DOI:10.1021/jo00824a025

Reference yield:

: 5672-83-3
Z-L-GluOMe

: 31874-53-0
Z-Gln(Dmb)-ONp

Guidance literature:: Multi-step reaction with 3 steps

1: (i) Na2(OCH₂CH₂OCH₃)2>, (ii) /BRN= 2567599/

2: aq. NaOH

3: DCC

With sodium hydroxide; dicyclohexyl-carbodiimide;
DOI:10.1021/jo00824a025

Reference yield:

: 31874-48-3
(S)-2-Benzyloxycarbonylamino-4-(2,4-dimethoxy-benzylcarbamoyl)-butyric acid methyl ester

: 31874-53-0
Z-Gln(Dmb)-ONp

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH

2: DCC

With sodium hydroxide; dicyclohexyl-carbodiimide;
DOI:10.1021/jo00824a025