tert-butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate

Base Information

Chemical Name:tert-butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate
CAS No.:1232423-55-0
Molecular Formula:C16H20BrN3O4
Molecular Weight:398.256
Hs Code.:
Mol file:1232423-55-0.mol

Synonyms:tert-butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate;Imidodicarbonic acid, 2-(5-bromo-3-ethynyl-2-pyrazinyl)-, 1,3-bis(1,1-dimethylethyl) ester;ditert-butyl 5-bromo-3-ethynylpyrazin-2-ylcarbamate

Suppliers and Price of tert-butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate 95%
250mg
$ 926.00

Matrix Scientific
tert-Butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate 95%
500mg
$ 1480.00

Chemenu
tert-ButylN-(5-bromo-3-ethynylpyrazin-2-yl)-N-(tert-butoxycarbonyl)carbamate 95%+
1g
$ 1268.00

Chemenu
tert-ButylN-(5-bromo-3-ethynylpyrazin-2-yl)-N-(tert-butoxycarbonyl)carbamate 95%+
250mg
$ 634.00

Chemenu
tert-ButylN-(5-bromo-3-ethynylpyrazin-2-yl)-N-(tert-butoxycarbonyl)carbamate 95%+
100mg
$ 380.00

Total 6 raw suppliers

Chemical Property of tert-butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate

Chemical Property:

PSA：81.62000
LogP:3.89700

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate

There total 5 articles about tert-butyl N-(5-bromo-3-ethynylpyrazin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1225062-32-7
tert-butyl N-tert-butoxycarbonyl-N-[5-bromo-3-((trimethylsilyl)ethyynyl)pyrazin-2-yl]carbamate

: 1232423-55-0
tert-butyl N-(5-bromo-3-ethynyl-pyrazin-2-yl)-N-tert-butoxycarbonyl-carbamate

Guidance literature:: tert-butyl N-tert-butoxycarbonyl-N-[5-bromo-3-((trimethylsilyl)ethyynyl)pyrazin-2-yl]carbamate; With sodium carbonate; In N,N-dimethyl-formamide; at 75 ℃; for 0.75h;

With water; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield: 94.0%

: 1402390-93-5
tert-butyl N-[5-bromo-3-(2-triisopropylsilylethynyl)pyrazin-2-yl]-N-(tert-butoxycarbonyl)carbamate

: 1232423-55-0
tert-butyl N-(5-bromo-3-ethynyl-pyrazin-2-yl)-N-tert-butoxycarbonyl-carbamate

Guidance literature:: tert-butyl N-[5-bromo-3-(2-triisopropylsilylethynyl)pyrazin-2-yl]-N-(tert-butoxycarbonyl)carbamate; With sodium carbonate; In N,N-dimethyl-formamide; at 75 ℃; for 0.75h;

With water; for 0.5h;

Reference yield: 78.0%

: 1232423-98-1
tert-butyl N-(3-ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-yl)N-tertbutoxycarbonyl-carbamate ?

: 1232423-55-0
tert-butyl N-(5-bromo-3-ethynyl-pyrazin-2-yl)-N-tert-butoxycarbonyl-carbamate

Guidance literature:: tert-butyl N-(3-ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-yl)N-tertbutoxycarbonyl-carbamate ?; With potassium carbonate; In ethanol; ethyl acetate; for 1h; Large scale;

In ethanol; water; ethyl acetate; for 2h; Large scale;